| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | 17 Again | $2,256,660 | - | 222 | - | $10,165 | $2,256,660 | 1 | Roadshow Films | true | false |
| 2 | 1 | Monsters vs. Aliens | $2,063,810 | -25.6% | 382 | - | $5,402 | $6,182,226 | 2 | Paramount Pictures International | false | false |
| 3 | - | The Boat That Rocked | $996,060 | - | 293 | - | $3,399 | $996,060 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | - | Race to Witch Mountain | $919,076 | - | 289 | - | $3,180 | $1,352,365 | 1 | Walt Disney Pictures | true | false |
| 5 | 2 | Knowing | $667,714 | -31.8% | 204 | - | $3,273 | $3,961,219 | 3 | Icon Film Distribution | false | false |
| 6 | - | Dragonball Evolution | $663,932 | - | 192 | - | $3,457 | $916,108 | 1 | 20th Century Fox International | true | false |
| 7 | 4 | The Pink Panther 2 | $305,129 | -36.2% | 198 | - | $1,541 | $1,005,003 | 2 | Sony Pictures Releasing | false | false |
| 8 | 6 | Duplicity | $261,174 | -43.5% | 153 | -62 | $1,707 | $3,261,039 | 4 | Universal Pictures International (UPI) | false | false |
| 9 | 3 | Confessions of a Shopaholic | $225,129 | -55.3% | 168 | -49 | $1,340 | $6,035,776 | 5 | Walt Disney Pictures | false | false |
| 10 | 5 | Paul Blart: Mall Cop | $212,069 | -54.9% | 166 | -30 | $1,277 | $3,026,463 | 4 | Sony Pictures Releasing | false | false |
| 11 | - | Fast & Furious | $185,075 | - | 33 | - | $5,608 | $185,075 | 1 | Universal Pictures International (UPI) | true | false |
| 12 | 7 | Inkheart | $179,205 | -43.8% | 135 | - | $1,327 | $651,321 | 2 | Roadshow Films | false | false |
| 13 | - | Mary and Max | $156,169 | - | 49 | - | $3,187 | $160,300 | 1 | Icon Film Distribution | true | false |
| 14 | 12 | Easy Virtue | $131,896 | -26.6% | 68 | +3 | $1,939 | $1,392,051 | 5 | Hopscotch Films | false | false |
| 15 | - | Elegy | $126,039 | - | 22 | - | $5,729 | $159,757 | 1 | Hopscotch Films | true | false |
| 16 | 11 | Slumdog Millionaire | $125,275 | -35.5% | 116 | -35 | $1,079 | $14,211,766 | 17 | Icon Film Distribution | false | false |
| 17 | 13 | Gran Torino | $114,247 | -28.6% | 88 | -42 | $1,298 | $11,339,981 | 12 | Roadshow Films | false | false |
| 18 | 16 | Summer Hours | $102,994 | +6% | 21 | +5 | $4,904 | $340,580 | 2 | Palace Films | false | false |
| 19 | 15 | The Reader | $99,025 | -22.4% | 45 | -6 | $2,200 | $2,632,637 | 8 | Roadshow Films | false | false |
| 20 | 8 | The Uninvited | $92,404 | -62.6% | 82 | -38 | $1,126 | $909,716 | 3 | Paramount Pictures International | false | false |
| 21 | - | Good | $36,809 | - | 22 | - | $1,673 | $36,809 | 1 | Paramount Pictures International | true | false |
| 22 | - | A Pain in the Ass | $17,946 | - | 12 | - | $1,495 | $17,946 | 1 | Sharmill Films | true | false |
| 23 | - | The Sniper | $5,523 | - | 1 | - | $5,523 | $5,523 | 1 | Rialto Distribution | true | false |
