| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Fast & Furious | $264,541 | -60.1% | 49 | -1 | $5,398 | $2,536,786 | 3 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | Knowing | $193,298 | -50% | 58 | - | $3,332 | $1,974,412 | 4 | Belga Films | false | false |
| 3 | - | He's Just Not That Into You | $190,470 | - | 35 | - | $5,442 | $362,033 | 1 | Paradiso Entertainment | true | false |
| 4 | - | Coco Before Chanel | $132,275 | - | 32 | - | $4,133 | $134,190 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 5 | 4 | OSS 117: Lost in Rio | $124,877 | -53.9% | 21 | - | $5,946 | $421,738 | 2 | Belga Films | false | false |
| 6 | - | The Last House on the Left | $101,951 | - | 27 | - | $3,775 | $107,257 | 1 | Universal Pictures International (UPI) | true | false |
| 7 | 3 | Monsters vs. Aliens | $95,254 | -71.5% | 88 | -5 | $1,082 | $1,278,861 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 5 | Beverly Hills Chihuahua | $70,980 | -72.8% | 52 | - | $1,365 | $807,709 | 4 | Walt Disney Pictures | false | false |
| 9 | 6 | Slumdog Millionaire | $68,093 | -43.6% | 40 | - | $1,702 | $3,239,779 | 15 | Cinéart | false | false |
| 10 | - | In the Electric Mist | $64,748 | - | 16 | - | $4,046 | $77,556 | 1 | Benelux Film Distributors | true | false |
| 11 | 7 | Safari | $46,858 | -55.8% | 17 | -1 | $2,756 | $471,826 | 4 | Alternative Films | false | false |
| 12 | 12 | S&M Judge | $41,578 | -46.9% | 19 | - | $2,188 | $917,754 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 13 | 10 | Duplicity | $39,678 | -57.4% | 33 | -5 | $1,202 | $823,286 | 5 | Universal Pictures International (UPI) | false | false |
| 14 | 8 | Make It Happen | $32,007 | -67.7% | 18 | +3 | $1,778 | $261,458 | 3 | Benelux Film Distributors | false | false |
| 15 | 9 | The Uninvited | $30,832 | -68.2% | 15 | - | $2,055 | $140,294 | 2 | Universal Pictures International (UPI) | false | false |
| 16 | 11 | Confessions of a Shopaholic | $22,681 | -73% | 34 | -3 | $667 | $879,402 | 6 | Walt Disney Pictures | false | false |
| 17 | 19 | Gran Torino | $20,769 | -37.5% | 17 | -8 | $1,221 | $1,043,756 | 9 | Warner Bros. | false | false |
| 18 | 16 | Chéri | $20,185 | -64.9% | 19 | -1 | $1,062 | $190,331 | 3 | Benelux Film Distributors | false | false |
| 19 | 14 | Marley & Me | $19,562 | -69% | 39 | -3 | $501 | $1,099,735 | 7 | 20th Century Fox International | false | false |
| 20 | 13 | Dragonball Evolution | $16,545 | -77.7% | 29 | -1 | $570 | $267,389 | 3 | 20th Century Fox International | false | false |
| 21 | 15 | Bolt | $15,477 | -73.1% | 40 | -11 | $386 | $3,017,770 | 11 | Walt Disney Pictures | false | false |
| 22 | 17 | Coco | $14,581 | -74.2% | 18 | -3 | $810 | $899,468 | 6 | Universal Pictures International (UPI) | false | false |
| 23 | 18 | The Reader | $13,232 | -60.9% | 17 | - | $778 | $759,748 | 8 | Benelux Film Distributors | false | false |
| 24 | 23 | Red Cliff | $10,139 | -59.7% | 11 | -5 | $921 | $301,345 | 5 | Belga Films | false | false |
| 25 | 28 | Welcome | $9,184 | -46.8% | 10 | -1 | $918 | $143,428 | 5 | Cinéart | false | false |
| 26 | 42 | Defiance | $8,820 | +102.4% | 3 | +2 | $2,940 | $241,810 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 27 | 22 | Ponyo | $8,319 | -68.8% | 9 | -1 | $924 | $67,808 | 3 | Cinéart | false | false |
| 28 | 35 | Linha de Passe | $8,275 | +21.4% | 8 | +1 | $1,034 | $25,031 | 2 | Cinéart | false | false |
| 29 | 21 | Hotel for Dogs | $8,005 | -72.1% | 23 | -4 | $348 | $1,188,888 | 10 | Universal Pictures International (UPI) | false | false |
| 30 | - | Che: Part Two | $7,609 | - | 3 | - | $2,536 | $15,203 | 1 | Cinéart | true | false |
| 31 | 27 | The Curious Case of Benjamin Button | $7,251 | -58.3% | 15 | -1 | $483 | $3,292,592 | 12 | Warner Bros. | false | false |
| 32 | 20 | Inkheart | $6,936 | -76.2% | 8 | -6 | $867 | $94,269 | 3 | Paradiso Entertainment | false | false |
| 33 | 32 | Katanga Business | $6,862 | -35% | 7 | - | $980 | $70,018 | 4 | Cinéart | false | false |
| 34 | 24 | District 13: Ultimatum | $6,621 | -72.2% | 11 | - | $601 | $297,863 | 5 | Belga Films | false | false |
| 35 | 25 | The True Story of Puss'N Boots | $5,008 | -74.5% | 15 | -2 | $333 | $74,186 | 4 | N/A | false | false |
| 36 | 31 | The Unborn | $4,628 | -58.4% | 8 | -4 | $578 | $273,039 | 6 | Universal Pictures International (UPI) | false | false |
| 37 | 30 | Lemo | $4,609 | -65.3% | 9 | -4 | $512 | $48,254 | 4 | N/A | false | false |
| 38 | 36 | The International | $3,593 | -46.6% | 4 | -3 | $898 | $345,424 | 7 | Sony Pictures Releasing | false | false |
| 39 | 33 | Milk | $3,588 | -59.7% | 11 | +2 | $326 | $352,723 | 9 | A-Film Distribution | false | false |
| 40 | 34 | Underworld: Rise of the Lycans | $3,553 | -58.9% | 3 | -2 | $1,184 | $92,301 | 6 | Sony Pictures Releasing | false | false |
| 41 | 29 | Watchmen | $3,333 | -76.3% | 2 | -13 | $1,666 | $1,184,064 | 8 | Universal Pictures International (UPI) | false | false |
| 42 | 37 | Frozen River | $3,295 | -50.4% | 4 | - | $823 | $12,743 | 2 | A-Film Distribution | false | false |
| 43 | 26 | La première étoile | $3,170 | -83.2% | 5 | -5 | $634 | $81,639 | 3 | Les Films de l'Elysée | false | false |
| 44 | 43 | Twilight | $1,231 | -70.5% | 2 | -2 | $615 | $3,342,577 | 22 | Belga Films | false | false |
| 45 | 40 | Princess Lillifee | $1,186 | -77.4% | 3 | - | $395 | $17,784 | 5 | Walt Disney Pictures | false | false |
| 46 | 46 | The Three Investigators and the Secret of Skeleton Island 2009 Re-release | $946 | -72.8% | 3 | -1 | $315 | $22,505 | 6 | Walt Disney Pictures | false | false |
| 47 | 47 | The Girl on the Train | $794 | -51.3% | 3 | -4 | $264 | $50,150 | 6 | Benelux Film Distributors | false | false |
| 48 | 50 | The Fall | $742 | -31.9% | 2 | - | $371 | $14,985 | 7 | Paradiso Entertainment | false | false |
| 49 | 54 | Tulpan | $499 | -22.9% | 1 | -1 | $499 | $18,698 | 8 | Benelux Film Distributors | false | false |
| 50 | - | The Most Distant Course 2009 Re-release | $276 | - | 1 | - | $276 | $276 | 1 | N/A | true | false |
| 51 | - | Doubt | $204 | - | 1 | - | $204 | $327,351 | 11 | Walt Disney Pictures | false | false |
| 52 | 56 | Leonera | $130 | -20.2% | 2 | -1 | $65 | $7,582 | 5 | A-Film Distribution | false | false |
