| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Fast & Furious | $61,812 | -37.4% | 9 | - | $6,868 | $221,160 | 2 | United International Pictures | false | false |
| 2 | 2 | Monsters vs. Aliens | $32,990 | +83.3% | 13 | - | $2,537 | $109,755 | 3 | United International Pictures | false | false |
| 3 | 3 | Slumdog Millionaire | $15,057 | -4.4% | 8 | - | $1,882 | $267,061 | 5 | Blitz | false | false |
| 4 | 4 | Gran Torino | $14,045 | +32.6% | 5 | - | $2,809 | $33,961 | 2 | Warner Bros. | false | false |
| 5 | 5 | Marley & Me | $10,226 | +18.3% | 6 | - | $1,704 | $86,346 | 4 | 20th Century Fox International | false | false |
| 6 | - | Race to Witch Mountain | $10,192 | - | 6 | - | $1,698 | $11,688 | 1 | Walt Disney Pictures | true | false |
| 7 | 7 | Confessions of a Shopaholic | $6,962 | +38.5% | 6 | - | $1,160 | $75,380 | 5 | Walt Disney Pictures | false | false |
| 8 | 6 | He's Just Not That Into You | $4,677 | -8.9% | 6 | - | $779 | $118,503 | 6 | Warner Bros. | false | false |
| 9 | 8 | The Reader | $3,361 | +13.6% | 2 | - | $1,680 | $61,047 | 6 | Cinemania Group | false | false |
| 10 | 10 | Hotel for Dogs | $3,344 | +149.2% | 8 | - | $418 | $65,070 | 6 | United International Pictures | false | false |
| 11 | 9 | Watchmen | $2,696 | +13.9% | 4 | - | $674 | $43,102 | 5 | United International Pictures | false | false |
| 12 | 12 | Inkheart | $1,505 | +64.1% | 4 | - | $376 | $14,153 | 4 | Warner Bros. | false | false |
| 13 | 13 | Twilight | $967 | +12.3% | 7 | - | $138 | $128,117 | 8 | N/A | false | false |
| 14 | 11 | Transporter 3 | $639 | -47.5% | 3 | - | $213 | $25,173 | 6 | Continental Film | false | false |
