| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Fast & Furious | $359,373 | -40.8% | 51 | -7 | $7,046 | $3,488,547 | 4 | United International Pictures | false | false |
| 2 | 2 | Monsters vs. Aliens | $265,276 | -9% | 62 | -10 | $4,278 | $2,605,973 | 4 | United International Pictures | false | false |
| 3 | - | The Strangers | $111,576 | - | 23 | - | $4,851 | $125,612 | 1 | N/A | true | false |
| 4 | - | Role Models | $99,425 | - | 30 | - | $3,314 | $99,425 | 1 | United International Pictures | true | false |
| 5 | 3 | Dragonball Evolution | $90,710 | -52.7% | 45 | -9 | $2,015 | $1,070,124 | 3 | 20th Century Fox International | false | false |
| 6 | 4 | Slumdog Millionaire | $82,549 | -26.3% | 25 | -1 | $3,301 | $1,524,774 | 9 | N/A | false | false |
| 7 | - | Earth | $76,812 | - | 11 | - | $6,982 | $99,181 | 1 | Walt Disney Pictures | true | false |
| 8 | 6 | Inkheart | $64,569 | -18.5% | 23 | -1 | $2,807 | $824,639 | 5 | N/A | false | false |
| 9 | 7 | Underworld: Rise of the Lycans | $49,639 | -33.6% | 27 | +1 | $1,838 | $958,777 | 5 | Sony Pictures Releasing | false | false |
| 10 | 5 | Confessions of a Shopaholic | $48,811 | -43.7% | 29 | -4 | $1,683 | $916,352 | 5 | Walt Disney Pictures | false | false |
| 11 | - | Catacombs | $48,284 | - | 15 | - | $3,218 | $55,888 | 1 | N/A | true | false |
| 12 | 11 | Paul Blart: Mall Cop | $44,148 | -11.7% | 21 | -4 | $2,102 | $1,211,197 | 7 | Sony Pictures Releasing | false | false |
| 13 | 10 | Balls of Fury | $37,533 | -31.5% | 11 | -1 | $3,412 | $130,503 | 2 | N/A | false | false |
| 14 | 9 | Pride and Glory | $30,361 | -53.9% | 19 | -1 | $1,597 | $129,907 | 2 | N/A | false | false |
| 15 | 8 | Sex Drive | $30,352 | -55% | 20 | -1 | $1,517 | $149,957 | 2 | N/A | false | false |
| 16 | 12 | Chaos | $13,301 | -59.5% | 10 | -5 | $1,330 | $199,090 | 3 | - | false | false |
| 17 | 14 | Smart People | $11,143 | -29.6% | 3 | - | $3,714 | $31,962 | 2 | N/A | false | false |
| 18 | 16 | The Painted Veil | $10,755 | -12% | 4 | - | $2,688 | $95,173 | 4 | N/A | false | false |
| 19 | - | Swing con son | $9,889 | - | 9 | - | $1,098 | $9,889 | 1 | N/A | true | false |
| 20 | 13 | Captivity | $6,060 | -76.7% | 10 | -2 | $606 | $286,101 | 5 | N/A | false | false |
| 21 | 15 | Bedtime Stories | $4,886 | -68.4% | 15 | -8 | $325 | $3,556,942 | 11 | Walt Disney Pictures | false | false |
| 22 | 17 | Gran Torino | $4,114 | -62.5% | 6 | -4 | $685 | $486,735 | 6 | Warner Bros. | false | false |
| 23 | 23 | The Nanny Diaries | $3,228 | +28.9% | 2 | - | $1,614 | $166,612 | 6 | N/A | false | false |
| 24 | 20 | The Duchess | $2,168 | -67.6% | 6 | +1 | $361 | $118,431 | 6 | United International Pictures | false | false |
| 25 | 22 | Tear This Heart Out | $2,091 | -16.9% | 1 | - | $2,091 | $93,100 | 6 | 20th Century Fox International | false | false |
| 26 | 21 | The International | $1,559 | -52.4% | 4 | - | $389 | $570,769 | 8 | Sony Pictures Releasing | false | false |
| 27 | 24 | Doubt | $1,402 | +33.8% | 4 | +1 | $350 | $320,447 | 9 | Walt Disney Pictures | false | false |
| 28 | - | The Big Sellout | $909 | - | 1 | - | $909 | $909 | 1 | N/A | true | false |
| 29 | 25 | The Pink Panther 2 | $56 | -91.6% | 1 | -1 | $56 | $991,694 | 10 | Sony Pictures Releasing | false | false |
