| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | X-Men Origins: Wolverine | $357,910 | -60% | 100 | - | $3,579 | $1,380,015 | 2 | 20th Century Fox International | false | false |
| 2 | - | Star Trek | $300,197 | - | 43 | - | $6,981 | $305,780 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | - | 17 Again | $188,580 | - | 34 | - | $5,546 | $273,145 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 4 | - | Sister Smile | $116,266 | - | 32 | - | $3,633 | $180,695 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 5 | 2 | Fast & Furious | $101,726 | -52.7% | 48 | -1 | $2,119 | $2,988,678 | 5 | Universal Pictures International (UPI) | false | false |
| 6 | 3 | He's Just Not That Into You | $100,740 | -47.5% | 36 | -1 | $2,798 | $757,307 | 3 | Paradiso Entertainment | false | false |
| 7 | 6 | My Bloody Valentine | $95,519 | -20.2% | 15 | - | $6,367 | $243,196 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 8 | 4 | Knowing | $88,547 | -48% | 41 | -15 | $2,159 | $2,353,340 | 6 | Belga Films | false | false |
| 9 | 5 | Coco Before Chanel | $71,296 | -44.7% | 32 | - | $2,228 | $409,673 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 10 | 8 | Incognito | $50,005 | -48.9% | 14 | - | $3,571 | $164,291 | 2 | Alternative Films | false | false |
| 11 | 7 | OSS 117: Lost in Rio | $48,722 | -55.6% | 21 | - | $2,320 | $630,553 | 4 | Belga Films | false | false |
| 12 | 9 | Monsters vs. Aliens | $45,713 | -53.2% | 75 | -8 | $609 | $1,476,938 | 6 | Universal Pictures International (UPI) | false | false |
| 13 | 12 | Slumdog Millionaire | $43,324 | -40.4% | 37 | +3 | $1,170 | $3,494,591 | 17 | Cinéart | false | false |
| 14 | 10 | Beverly Hills Chihuahua | $40,274 | -55.4% | 51 | - | $789 | $984,565 | 6 | Walt Disney Pictures | false | false |
| 15 | 11 | The Last House on the Left | $36,536 | -53.3% | 23 | -3 | $1,588 | $258,832 | 3 | Universal Pictures International (UPI) | false | false |
| 16 | - | The Boat That Rocked | $28,890 | - | 28 | - | $1,031 | $47,378 | 1 | Universal Pictures International (UPI) | true | false |
| 17 | - | Je l'aimais | $26,455 | - | 12 | - | $2,204 | $33,952 | 1 | N/A | true | false |
| 18 | 13 | In the Electric Mist | $21,578 | -59.6% | 13 | -3 | $1,659 | $181,475 | 3 | Benelux Film Distributors | false | false |
| 19 | 14 | S&M Judge | $20,561 | -54.1% | 15 | -4 | $1,370 | $1,027,353 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 20 | 15 | The Boy in the Striped Pajamas | $17,774 | -47.4% | 11 | - | $1,615 | $66,687 | 2 | Walt Disney Pictures | false | false |
| 21 | 20 | London River | $10,928 | -49.4% | 12 | - | $910 | $38,290 | 2 | ABC Distribution | false | false |
| 22 | 17 | Duplicity | $10,729 | -60.1% | 9 | -10 | $1,192 | $897,269 | 7 | Universal Pictures International (UPI) | false | false |
| 23 | 16 | Make It Happen | $9,876 | -66.6% | 15 | -2 | $658 | $316,547 | 5 | Benelux Film Distributors | false | false |
| 24 | - | The Chaser | $8,255 | - | 5 | - | $1,651 | $14,196 | 1 | Cinéart | true | false |
| 25 | 25 | The Reader | $7,391 | -40.3% | 13 | -3 | $568 | $815,263 | 10 | Benelux Film Distributors | false | false |
| 26 | 21 | Chéri | $7,116 | -52.9% | 10 | +1 | $711 | $232,989 | 5 | Benelux Film Distributors | false | false |
| 27 | 22 | Gran Torino | $7,009 | -51.3% | 10 | -7 | $700 | $1,104,540 | 11 | Warner Bros. | false | false |
| 28 | 18 | Safari | $6,408 | -75.8% | 12 | -4 | $534 | $527,875 | 6 | Alternative Films | false | false |
| 29 | 23 | Bolt | $5,571 | -60.7% | 27 | - | $206 | $3,133,877 | 13 | Walt Disney Pictures | false | false |
| 30 | 19 | Le missionnaire | $4,635 | -78.6% | 11 | -3 | $421 | $27,956 | 2 | N/A | false | false |
| 31 | 33 | Defiance | $3,454 | -37.8% | 4 | +1 | $863 | $264,381 | 10 | Kinepolis Film Distribution (KFD) | false | false |
| 32 | 27 | Ponyo | $3,288 | -69.1% | 8 | - | $411 | $84,588 | 5 | Cinéart | false | false |
| 33 | 28 | Welcome | $3,055 | -65.6% | 8 | -1 | $381 | $164,942 | 7 | Cinéart | false | false |
| 34 | 24 | Celle que j'aime | $2,984 | -78% | 3 | -4 | $994 | $20,111 | 2 | Les Films de l'Elysée | false | false |
| 35 | 39 | The International | $2,806 | -24.9% | 3 | -1 | $935 | $353,332 | 9 | Sony Pictures Releasing | false | false |
| 36 | 37 | Frozen River | $2,530 | -34.7% | 4 | - | $632 | $22,797 | 4 | A-Film Distribution | false | false |
| 37 | 31 | Katanga Business | $2,304 | -64.4% | 7 | - | $329 | $88,003 | 6 | Cinéart | false | false |
| 38 | 41 | Milk | $2,296 | -36% | 9 | +1 | $255 | $372,121 | 11 | A-Film Distribution | false | false |
| 39 | 42 | Food Beware: The French Organic Revolution | $2,045 | -39.3% | 6 | - | $340 | $33,255 | 4 | N/A | false | false |
| 40 | 35 | Hotel for Dogs | $1,841 | -60.9% | 15 | -3 | $122 | $1,232,318 | 12 | Universal Pictures International (UPI) | false | false |
| 41 | 26 | The Uninvited | $1,621 | -86.1% | 2 | -8 | $810 | $163,379 | 4 | Universal Pictures International (UPI) | false | false |
| 42 | 29 | Confessions of a Shopaholic | $1,589 | -77.6% | 9 | -5 | $176 | $919,771 | 8 | Walt Disney Pictures | false | false |
| 43 | 36 | The Unborn | $1,164 | -71.6% | 4 | -1 | $291 | $287,562 | 8 | Universal Pictures International (UPI) | false | false |
| 44 | - | Française | $1,052 | - | 2 | - | $526 | $1,118 | 1 | N/A | true | false |
| 45 | 48 | Watchmen | $972 | -33.7% | 2 | +1 | $486 | $1,223,314 | 10 | Universal Pictures International (UPI) | false | false |
| 46 | - | Jar City | $737 | - | 2 | - | $368 | $874 | 1 | N/A | true | false |
| 47 | 30 | Linha de Passe | $726 | -89.3% | 5 | -3 | $145 | $37,528 | 4 | Cinéart | false | false |
| 48 | - | Birdwatchers | $546 | - | 1 | - | $546 | $3,543 | 10 | ABC Distribution | false | false |
| 49 | 44 | Inkheart | $500 | -83.8% | 2 | -1 | $250 | $104,002 | 5 | Paradiso Entertainment | false | false |
| 50 | 50 | The Fall | $442 | -50.7% | 3 | +1 | $147 | $17,372 | 9 | Paradiso Entertainment | false | false |
| 51 | 49 | Twilight | $426 | -54.5% | 1 | - | $426 | $3,445,062 | 24 | Belga Films | false | false |
