| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Haunting in Connecticut | $204,065 | - | 285 | - | $716 | $1,664,141 | 4 | Gussi Films | false | false |
| 2 | - | Race to Witch Mountain | $176,193 | - | 279 | - | $631 | $3,537,984 | 7 | Walt Disney Pictures | false | false |
| 3 | - | Fast & Furious | $167,363 | - | 392 | - | $426 | $12,809,224 | 6 | Universal Pictures International (UPI) | false | false |
| 4 | - | Monsters vs. Aliens | $150,361 | - | 407 | - | $369 | $10,269,741 | 6 | Paramount Pictures International | false | false |
| 5 | - | Knowing | $139,872 | - | 186 | - | $752 | $4,285,868 | 7 | Corazón Films | false | false |
| 6 | - | Amar a morir | $134,783 | - | 257 | - | $524 | $2,179,854 | 5 | Gussi Films | false | false |
| 7 | - | Igor | $119,123 | - | 249 | - | $478 | $317,289 | 3 | Videocine | false | false |
| 8 | - | I Love You, Man | $109,591 | - | 185 | - | $592 | $269,060 | 3 | Paramount Pictures International | false | false |
| 9 | - | Duplicity | $108,258 | - | 161 | - | $672 | $1,511,113 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | - | Gran Torino | $96,839 | - | 156 | - | $620 | $1,826,844 | 7 | Warner Bros. | false | false |
| 11 | - | El libro de piedra | $76,813 | - | 155 | - | $495 | $497,915 | 4 | N/A | false | false |
| 12 | - | Slumdog Millionaire | $66,878 | - | 112 | - | $597 | $6,169,615 | 12 | Gussi Films | false | false |
| 13 | - | The Reader | $53,786 | - | 85 | - | $632 | $819,046 | 6 | Gussi Films | false | false |
| 14 | - | The Accidental Husband | $38,764 | - | 92 | - | $421 | $1,181,969 | 6 | Walt Disney Pictures | false | false |
| 15 | - | Dragonball Evolution | $23,951 | - | 181 | - | $132 | $2,369,182 | 5 | 20th Century Fox International | false | false |
| 16 | - | In Bruges | $21,705 | - | 46 | - | $471 | $123,464 | 8 | Corazón Films | false | false |
| 17 | - | The International | $21,433 | - | 62 | - | $345 | $839,558 | 8 | Sony Pictures Releasing | false | false |
| 18 | - | Surveillance | $19,751 | - | 98 | - | $201 | $53,984 | 3 | N/A | false | false |
| 19 | - | The Children of Huang Shi | $19,387 | - | 30 | - | $646 | $34,374 | 3 | Gussi Films | false | false |
| 20 | - | The Unborn | $17,815 | - | 61 | - | $292 | $5,214,170 | 9 | Universal Pictures International (UPI) | false | false |
| 21 | - | 12 Rounds | $15,317 | - | 52 | - | $294 | $183,162 | 4 | 20th Century Fox International | false | false |
| 22 | - | Paul Blart: Mall Cop | $14,714 | - | 28 | - | $525 | $2,190,060 | 9 | Sony Pictures Releasing | false | false |
| 23 | - | Paraiso Travel | $14,142 | - | 51 | - | $277 | $27,466 | 3 | N/A | false | false |
| 24 | - | Another Egg and Chicken Movie | $13,417 | - | 103 | - | $130 | $8,562,812 | 8 | Videocine | false | false |
| 25 | - | Insignificant Things | $10,256 | - | 55 | - | $186 | $178,718 | 4 | Warner Bros. | false | false |
| 26 | - | Borderland | $9,609 | - | 62 | - | $154 | $165,258 | 5 | Videocine | false | false |
| 27 | - | Elegy | $9,542 | - | 48 | - | $198 | $216,717 | 9 | Corazón Films | false | false |
| 28 | - | The Secret Life of Bees | $8,904 | - | 30 | - | $296 | $157,273 | 9 | 20th Century Fox International | false | false |
| 29 | - | Rachel Getting Married | $8,030 | - | 7 | - | $1,147 | $98,795 | 8 | Sony Pictures Releasing | false | false |
| 30 | - | Cherry Blossoms | $6,278 | - | 12 | - | $523 | $46,681 | 4 | N/A | false | false |
| 31 | - | Underworld: Rise of the Lycans | $2,358 | - | 5 | - | $471 | $3,843,876 | 14 | Sony Pictures Releasing | false | false |
| 32 | - | Desierto adentro | $1,954 | - | 12 | - | $162 | $48,966 | 9 | Gussi Films | false | false |
| 33 | - | Standard Operating Procedure | $265 | - | 5 | - | $53 | $8,606 | 6 | N/A | false | false |
| 34 | - | Dark Matter | $244 | - | 2 | - | $122 | $29,597 | 7 | David Distribucion | false | false |
| 35 | - | The Pink Panther 2 | $146 | - | 1 | - | $146 | $2,177,789 | 11 | Sony Pictures Releasing | false | false |
