| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | X-Men Origins: Wolverine | $38,513 | -54.4% | 21 | -5 | $1,833 | $196,423 | 2 | 20th Century Fox International | false | false |
| 2 | - | The Unborn | $36,968 | - | 15 | - | $2,464 | $36,968 | 1 | United International Pictures | true | false |
| 3 | - | Star Trek | $22,745 | - | 12 | - | $1,895 | $22,745 | 1 | United International Pictures | true | false |
| 4 | 4 | Paul Blart: Mall Cop | $18,260 | +3.9% | 14 | +3 | $1,304 | $213,279 | 5 | Sony Pictures Releasing | false | false |
| 5 | - | Knowing | $16,472 | - | 12 | - | $1,372 | $16,472 | 1 | N/A | true | false |
| 6 | 5 | Underworld: Rise of the Lycans | $13,189 | -13% | 10 | -11 | $1,318 | $307,230 | 7 | Sony Pictures Releasing | false | false |
| 7 | 2 | Race to Witch Mountain | $8,504 | -61.7% | 14 | -1 | $607 | $129,277 | 4 | Walt Disney Pictures | false | false |
| 8 | 3 | 17 Again | $6,723 | -67.6% | 10 | -3 | $672 | $77,063 | 3 | Warner Bros. | false | false |
| 9 | - | Milk | $6,205 | - | 8 | - | $775 | $6,205 | 1 | United International Pictures | true | false |
| 10 | 6 | Fast & Furious | $2,641 | -76% | 7 | -4 | $377 | $344,784 | 6 | United International Pictures | false | false |
| 11 | 11 | Slumdog Millionaire | $1,377 | -55.9% | 1 | - | $1,377 | $96,509 | 8 | N/A | false | false |
| 12 | 7 | Earth | $1,301 | -79% | 4 | - | $325 | $23,782 | 3 | Walt Disney Pictures | false | false |
| 13 | 9 | The Flock | $910 | -82.5% | 4 | -2 | $227 | $9,653 | 2 | N/A | false | false |
| 14 | 10 | Monsters vs. Aliens | $481 | -86.1% | 2 | -3 | $240 | $153,317 | 6 | United International Pictures | false | false |
| 15 | 8 | Rudo y Cursi | $426 | -92.8% | 4 | -7 | $106 | $10,729 | 2 | United International Pictures | false | false |
| 16 | 13 | The Mist | $30 | -96.7% | 1 | -3 | $30 | $8,928 | 3 | N/A | false | false |
