| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Angels & Demons | $710,077 | - | 100 | - | $7,100 | $790,288 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Star Trek | $66,251 | -65.3% | 78 | - | $849 | $333,277 | 2 | Paramount Pictures International | false | false |
| 3 | 2 | X-Men Origins: Wolverine | $30,759 | -64.3% | 73 | -7 | $421 | $452,169 | 3 | 20th Century Fox International | false | false |
| 4 | - | Observe and Report | $28,568 | - | 30 | - | $952 | $28,568 | 1 | Warner Bros. | true | false |
| 5 | 3 | The Boat That Rocked | $14,388 | -60% | 37 | -3 | $388 | $67,958 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | Coraline | $9,196 | -74.4% | 42 | -13 | $218 | $191,275 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | 5 | Dark Planet: Rebellion | $5,383 | -77.5% | 39 | -36 | $138 | $611,952 | 4 | Gemini Films | false | false |
| 8 | - | Easy Virtue | $4,361 | - | 11 | - | $396 | $92,346 | 4 | Aurora | false | false |
| 9 | 6 | Race to Witch Mountain | $2,736 | -75.6% | 19 | -19 | $144 | $200,905 | 4 | Walt Disney Pictures | false | false |
| 10 | 7 | I Love You, Man | $2,409 | -72.3% | 7 | -12 | $344 | $233,763 | 6 | Paramount Pictures International | false | false |
| 11 | - | Monsters vs. Aliens | $1,946 | - | 2 | - | $973 | $807,769 | 9 | Paramount Pictures International | false | false |
| 12 | 10 | Fast & Furious | $1,153 | -73.2% | 19 | -16 | $60 | $1,007,293 | 6 | Universal Pictures International (UPI) | false | false |
| 13 | - | 12 Rounds | $382 | - | 4 | - | $95 | $33,499 | 5 | 20th Century Fox International | false | false |
| 14 | - | He's Just Not That Into You | $211 | - | 3 | - | $70 | $290,724 | 7 | Warner Bros. | false | false |
| 15 | - | Dragonball Evolution | $55 | - | 1 | - | $55 | $44,350 | 7 | 20th Century Fox International | false | false |
| 16 | - | Gran Torino | $10 | - | 1 | - | $10 | $7,469 | 6 | Warner Bros. | false | false |
