| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Night at the Museum: Battle of the Smithsonian | $42,596 | - | 9 | - | $4,732 | $42,596 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Angels & Demons | $35,876 | -48.5% | 8 | - | $4,484 | $127,152 | 2 | Sony Pictures Releasing | false | false |
| 3 | 2 | X-Men Origins: Wolverine | $7,579 | -52.3% | 8 | - | $947 | $134,124 | 4 | 20th Century Fox International | false | false |
| 4 | - | Changeling | $2,730 | - | 4 | - | $682 | $2,730 | 1 | United International Pictures | true | false |
| 5 | 4 | Confessions of a Shopaholic | $2,017 | -64.6% | 2 | -2 | $1,008 | $20,227 | 7 | Walt Disney Pictures | false | false |
| 6 | 3 | Star Trek | $1,939 | -67.8% | 4 | -2 | $484 | $27,914 | 3 | United International Pictures | false | false |
| 7 | - | Lonely Hearts | $1,731 | - | 1 | - | $1,731 | $1,731 | 1 | - | true | false |
| 8 | 5 | The Boy in the Striped Pajamas | $1,335 | -69.8% | 2 | -1 | $667 | $29,334 | 7 | Walt Disney Pictures | false | false |
| 9 | 7 | Donkey Xote | $1,226 | -55.3% | 2 | - | $613 | $14,818 | 4 | - | false | false |
| 10 | 6 | Race to Witch Mountain | $986 | -66.3% | 2 | -1 | $493 | $109,141 | 9 | Walt Disney Pictures | false | false |
| 11 | 14 | The Diving Bell and the Butterfly | $897 | +35.5% | 1 | - | $897 | $13,323 | 5 | N/A | false | false |
| 12 | 9 | Jonas Brothers: The 3D Concert Experience | $732 | -67.9% | 1 | - | $732 | $22,952 | 5 | Walt Disney Pictures | false | false |
| 13 | 10 | Lassie | $664 | -68.2% | 2 | - | $332 | $6,514 | 3 | - | false | false |
| 14 | - | Leonera | $549 | - | 1 | - | $549 | $549 | 1 | N/A | true | false |
| 15 | 11 | Captivity | $430 | -70.1% | 1 | - | $430 | $29,825 | 6 | - | false | false |
