| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Night at the Museum: Battle of the Smithsonian | $2,552,202 | - | 488 | - | $5,229 | $2,552,604 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Angels & Demons | $2,286,323 | -39.4% | 509 | - | $4,491 | $7,465,347 | 2 | Sony Pictures Releasing | false | false |
| 3 | 2 | X-Men Origins: Wolverine | $699,218 | -54% | 432 | -88 | $1,618 | $12,064,801 | 4 | 20th Century Fox International | false | false |
| 4 | 3 | Diva 2009 Re-release | $389,226 | -31% | 175 | -12 | $2,224 | $6,503,974 | 6 | N/A | false | false |
| 5 | - | Budapest | $120,938 | - | 39 | - | $3,100 | $120,938 | 1 | N/A | true | false |
| 6 | 4 | Star Trek | $120,310 | -66.7% | 146 | -103 | $824 | $1,618,121 | 3 | Paramount Pictures International | false | false |
| 7 | 5 | Monsters vs. Aliens | $47,180 | -63.1% | 70 | -50 | $674 | $6,520,920 | 8 | Paramount Pictures International | false | false |
| 8 | - | The Invisible Woman | $43,476 | - | 50 | - | $869 | $43,476 | - | Warner Bros. | - | false |
| 9 | 10 | Simonal: Ninguém Sabe o Duro que Dei | $39,584 | -20.9% | 23 | -1 | $1,721 | $118,651 | 2 | N/A | false | false |
| 10 | 9 | Lust, Caution | $38,504 | -31.4% | 12 | - | $3,208 | $116,793 | 2 | Europa Filmes | false | false |
| 11 | 7 | Fast & Furious | $35,933 | -63.4% | 89 | -62 | $403 | $9,583,725 | 8 | Universal Pictures International (UPI) | false | false |
| 12 | 6 | Garfield's Fun Fest | $28,418 | -72.2% | 105 | -5 | $270 | $594,152 | 4 | PlayArte Pictures | false | false |
| 13 | - | Jonas Brothers: The 3D Concert Experience | $20,637 | - | 24 | - | $859 | $20,637 | - | Walt Disney Pictures | - | false |
| 14 | 8 | Defiance | $16,210 | -73.3% | 17 | -19 | $953 | $259,548 | 3 | N/A | false | false |
| 15 | 15 | Che: Part One | $14,640 | -11.3% | 18 | -6 | $813 | $621,143 | 9 | Europa Filmes | false | false |
| 16 | 14 | New in Town | $9,460 | -69.8% | 12 | -21 | $788 | $468,665 | 4 | N/A | false | false |
| 17 | 13 | I Love You, Man | $7,277 | -76.8% | 16 | -18 | $454 | $483,250 | 5 | Paramount Pictures International | false | false |
| 18 | 11 | Race to Witch Mountain | $6,820 | -82.6% | 25 | -25 | $272 | $1,055,658 | 6 | Walt Disney Pictures | false | false |
| 19 | 23 | Underworld: Rise of the Lycans | $6,441 | -15.7% | 25 | - | $257 | $1,391,384 | 6 | Sony Pictures Releasing | false | false |
| 20 | 22 | Gran Torino | $5,449 | -29.4% | 7 | -4 | $778 | $1,645,640 | 10 | Warner Bros. | false | false |
| 21 | 16 | He's Just Not That Into You | $5,301 | -56.1% | 8 | -15 | $662 | $3,684,147 | 9 | PlayArte Pictures | false | false |
| 22 | 17 | Happy-Go-Lucky | $5,276 | -52.3% | 5 | -7 | $1,055 | $230,195 | 9 | Imagem Filmes | false | false |
| 23 | 12 | Knowing | $5,234 | -86% | 22 | -42 | $237 | $4,098,018 | 7 | Paris Filmes | false | false |
| 24 | 18 | The Class | $4,834 | -56.2% | 12 | -3 | $402 | $545,428 | 11 | Imovision | false | false |
| 25 | 19 | Confessions of a Shopaholic | $4,620 | -53.3% | 8 | -2 | $577 | $747,162 | 7 | Walt Disney Pictures | false | false |
| 26 | 32 | Rachel Getting Married | $4,431 | +129.2% | 7 | +1 | $633 | $322,015 | 15 | Sony Pictures Releasing | false | false |
| 27 | 20 | The Haunting in Connecticut | $3,700 | -57.4% | 13 | -12 | $284 | $1,575,131 | 6 | N/A | false | false |
| 28 | 24 | I Hate Valentine's Day | $3,057 | -56.2% | 8 | -7 | $382 | $773,464 | 5 | PlayArte Pictures | false | false |
| 29 | 41 | Personal Effects | $2,492 | +177.2% | 3 | - | $830 | $157,248 | 8 | Imagem Filmes | false | false |
| 30 | 27 | Waltz with Bashir | $2,190 | -30.6% | 8 | - | $273 | $88,865 | 8 | Sony Pictures Releasing | false | false |
| 31 | 26 | If I Were You 2 | $2,102 | -40.5% | 4 | +1 | $525 | $24,410,697 | 21 | 20th Century Fox International | false | false |
| 32 | 25 | Slumdog Millionaire | $1,858 | -52.1% | 13 | -6 | $142 | $6,210,439 | 12 | Europa Filmes | false | false |
| 33 | 29 | Earth | $1,404 | -49.2% | 8 | -1 | $175 | $87,979 | 5 | Walt Disney Pictures | false | false |
| 34 | 39 | O Menino da Porteira | $853 | -12.2% | 7 | - | $121 | $1,863,136 | 12 | Sony Pictures Releasing | false | false |
| 35 | 35 | Doubt | $795 | -48.8% | 3 | -1 | $265 | $755,818 | 16 | Walt Disney Pictures | false | false |
| 36 | 28 | The Happy Cricket and the Giant Bugs | $723 | -74.7% | 4 | -7 | $180 | $833,278 | 20 | 20th Century Fox International | false | false |
| 37 | 36 | Beverly Hills Chihuahua | $354 | -65.2% | 3 | -1 | $118 | $589,366 | 15 | Walt Disney Pictures | false | false |
| 38 | 37 | Ashes of Time | $317 | -68.5% | 1 | -3 | $317 | $27,531 | 4 | N/A | false | false |
| 39 | 21 | Dragonball Evolution | $295 | -96.3% | 2 | -34 | $147 | $1,745,575 | 7 | 20th Century Fox International | false | false |
| 40 | 44 | Frozen River | $252 | +31.9% | 2 | - | $126 | $40,315 | 14 | Sony Pictures Releasing | false | false |
