| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Angels & Demons | $22,473 | -54.5% | 4 | - | $5,618 | $97,257 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Night at the Museum: Battle of the Smithsonian | $17,960 | - | 5 | - | $3,592 | $17,960 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | Coraline | $6,288 | -31.6% | 1 | - | $6,288 | $19,047 | 2 | United International Pictures | false | false |
| 4 | - | The Last House on the Left | $6,207 | - | 2 | - | $3,103 | $6,207 | 1 | United International Pictures | true | false |
| 5 | 3 | Star Trek | $3,859 | -31.3% | 3 | -1 | $1,286 | $35,446 | 3 | United International Pictures | false | false |
| 6 | 5 | 17 Again | $2,977 | +5.1% | 2 | - | $1,488 | $44,893 | 5 | Warner Bros. | false | false |
| 7 | 4 | X-Men Origins: Wolverine | $2,373 | -21.9% | 2 | -2 | $1,186 | $39,463 | 4 | 20th Century Fox International | false | false |
| 8 | 7 | Observe and Report | $1,377 | -25.4% | 2 | - | $688 | $13,340 | 3 | Warner Bros. | false | false |
| 9 | 9 | Crank: High Voltage | $1,344 | +29.7% | 1 | -2 | $1,344 | $49,777 | 6 | N/A | false | false |
| 10 | 11 | I Love You, Man | $1,240 | +77.7% | 2 | - | $620 | $63,454 | 5 | United International Pictures | false | false |
| 11 | 12 | The Boat That Rocked | $677 | -0.1% | 1 | -1 | $677 | $9,761 | 4 | United International Pictures | false | false |
