| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Terminator Salvation | $677,579 | - | 110 | - | $6,159 | $677,579 | 1 | - | true | false |
| 2 | 1 | Night at the Museum: Battle of the Smithsonian | $53,390 | -66.8% | 94 | - | $567 | $713,305 | 3 | Gemini Films | false | false |
| 3 | 2 | Angels & Demons | $44,922 | -62% | 92 | -8 | $488 | $1,536,157 | 4 | Sony Pictures Releasing | false | false |
| 4 | 3 | Star Trek | $2,692 | -78.8% | 23 | -49 | $117 | $402,510 | 5 | Paramount Pictures International | false | false |
| 5 | 4 | Observe and Report | $1,820 | -67.2% | 21 | -8 | $86 | $64,089 | 4 | Warner Bros. | false | false |
| 6 | 9 | Monsters vs. Aliens | $1,390 | +27.8% | 1 | -2 | $1,390 | $834,266 | 12 | Paramount Pictures International | false | false |
| 7 | 7 | I Love You, Man | $1,369 | -51.5% | 2 | -2 | $684 | $243,694 | 9 | Paramount Pictures International | false | false |
| 8 | 8 | Coraline | $1,105 | -47.2% | 12 | -7 | $92 | $202,055 | 6 | Universal Pictures International (UPI) | false | false |
| 9 | 5 | X-Men Origins: Wolverine | $597 | -82.6% | 7 | -21 | $85 | $478,116 | 6 | 20th Century Fox International | false | false |
| 10 | - | 12 Rounds | $151 | - | 1 | - | $151 | $35,169 | 8 | 20th Century Fox International | false | false |
