| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Up | $775,504 | +2.8% | 160 | -5 | $4,846 | $1,799,872 | 2 | Walt Disney Pictures | false | false |
| 2 | 2 | Terminator Salvation | $326,548 | -29.9% | 115 | - | $2,839 | $1,035,115 | 2 | Sony Pictures Releasing | false | false |
| 3 | 3 | Angels & Demons | $126,515 | -17.3% | 77 | -26 | $1,643 | $2,445,101 | 5 | Sony Pictures Releasing | false | false |
| 4 | 4 | Night at the Museum: Battle of the Smithsonian | $125,532 | -16.5% | 111 | +10 | $1,130 | $1,587,469 | 4 | 20th Century Fox International | false | false |
| 5 | - | Transporter 3 | $78,015 | - | 48 | - | $1,625 | $78,015 | 1 | Cineplex | true | false |
| 6 | - | Death Defying Acts | $60,056 | - | 32 | - | $1,876 | $60,056 | 1 | Cine Colombia | true | false |
| 7 | 8 | The Unborn | $32,117 | +239.4% | 27 | +9 | $1,189 | $367,819 | 6 | United International Pictures | false | false |
| 8 | 6 | Duplicity | $21,520 | -11.9% | 24 | -1 | $896 | $137,192 | 3 | United International Pictures | false | false |
| 9 | - | The Class | $13,702 | - | 12 | - | $1,141 | $14,153 | 1 | - | true | false |
| 10 | 7 | X-Men Origins: Wolverine | $6,831 | -45.7% | 11 | -7 | $621 | $1,619,023 | 7 | 20th Century Fox International | false | false |
| 11 | 9 | Venus 2009 Re-release | $6,292 | -16.2% | 4 | +1 | $1,573 | $45,873 | 4 | Cine Colombia | false | false |
| 12 | 5 | Righteous Kill | $4,225 | -85.8% | 5 | -31 | $845 | $158,621 | 3 | Cine Colombia | false | false |
| 13 | 19 | Monsters vs. Aliens | $3,582 | +326.9% | 6 | -3 | $597 | $2,082,836 | 11 | United International Pictures | false | false |
| 14 | 11 | Frozen River | $1,873 | -53.9% | 3 | - | $624 | $24,326 | 4 | Sony Pictures Releasing | false | false |
| 15 | 10 | Hannah Montana: The Movie | $1,839 | -73.3% | 12 | -13 | $153 | $539,732 | 7 | Walt Disney Pictures | false | false |
| 16 | 12 | Happy-Go-Lucky | $1,505 | -58.1% | 3 | -2 | $501 | $18,259 | 3 | Cineplex | false | false |
| 17 | 17 | Star Trek | $959 | -29.3% | 3 | -1 | $319 | $276,315 | 6 | United International Pictures | false | false |
| 18 | 13 | Earth | $920 | -61.2% | 16 | -1 | $57 | $236,911 | 8 | Walt Disney Pictures | false | false |
| 19 | 18 | Race to Witch Mountain | $480 | -51.1% | 2 | -1 | $240 | $1,404,257 | 12 | Walt Disney Pictures | false | false |
| 20 | 20 | Paul Blart: Mall Cop | $317 | -42.9% | 2 | - | $158 | $140,588 | 6 | Sony Pictures Releasing | false | false |
