| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Terminator Salvation | $201,892 | -70.2% | 110 | - | $1,835 | $1,101,431 | 2 | - | false | false |
| 2 | - | The Hangover | $193,331 | - | 45 | - | $4,296 | $323,545 | 1 | Warner Bros. | true | false |
| 3 | - | State of Play | $68,447 | - | 35 | - | $1,955 | $68,447 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | 2 | Night at the Museum: Battle of the Smithsonian | $21,047 | -60.6% | 75 | -19 | $280 | $758,109 | 4 | Gemini Films | false | false |
| 5 | 3 | Angels & Demons | $15,626 | -65.2% | 53 | -39 | $294 | $1,561,294 | 5 | Sony Pictures Releasing | false | false |
| 6 | 6 | Monsters vs. Aliens | $3,020 | +117.3% | 4 | +3 | $755 | $838,735 | 13 | Paramount Pictures International | false | false |
| 7 | 4 | Star Trek | $2,514 | -6.6% | 17 | -6 | $147 | $406,596 | 6 | Paramount Pictures International | false | false |
| 8 | 7 | I Love You, Man | $790 | -42.3% | 2 | - | $395 | $244,972 | 10 | Paramount Pictures International | false | false |
| 9 | - | Race to Witch Mountain | $640 | - | 4 | - | $160 | $203,636 | 8 | Walt Disney Pictures | false | false |
| 10 | 8 | Coraline | $530 | -52% | 3 | -9 | $176 | $203,216 | 7 | Universal Pictures International (UPI) | false | false |
| 11 | 5 | Observe and Report | $523 | -71.3% | 5 | -16 | $104 | $66,307 | 5 | Warner Bros. | false | false |
| 12 | 9 | X-Men Origins: Wolverine | $520 | -12.9% | 3 | -4 | $173 | $483,429 | 7 | 20th Century Fox International | false | false |
| 13 | 10 | 12 Rounds | $75 | -50.3% | 1 | - | $75 | $35,702 | 9 | 20th Century Fox International | false | false |
