| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Terminator Salvation | $186,911 | -42% | 100 | - | $1,869 | $672,729 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Up | $110,828 | - | 26 | - | $4,262 | $145,368 | 1 | Walt Disney Pictures | true | false |
| 3 | 2 | Angels & Demons | $41,840 | -44.7% | 46 | -25 | $909 | $1,384,534 | 5 | Sony Pictures Releasing | false | false |
| 4 | 3 | Night at the Museum: Battle of the Smithsonian | $24,928 | -40.3% | 18 | -3 | $1,384 | $269,701 | 4 | 20th Century Fox International | false | false |
| 5 | 4 | Ghosts of Girlfriends Past | $7,908 | -22.1% | 8 | -2 | $988 | $87,585 | 4 | Warner Bros. | false | false |
| 6 | - | Talento de barrio | $7,633 | - | 8 | - | $954 | $10,583 | 1 | N/A | true | false |
| 7 | 5 | Duplicity | $3,728 | -56% | 2 | -8 | $1,864 | $39,734 | 3 | United International Pictures | false | false |
| 8 | 6 | Hannah Montana: The Movie | $1,209 | -72.8% | 5 | -3 | $241 | $64,545 | 5 | Walt Disney Pictures | false | false |
| 9 | 9 | The Unborn | $600 | -32.2% | 2 | -2 | $300 | $89,168 | 6 | United International Pictures | false | false |
| 10 | 10 | Doubt | $328 | -24.4% | 1 | - | $328 | $11,799 | 5 | Walt Disney Pictures | false | false |
| 11 | 8 | Knowing | $301 | -71.1% | 1 | -2 | $301 | $62,241 | 6 | N/A | false | false |
| 12 | 11 | X-Men Origins: Wolverine | $95 | -37.5% | 2 | - | $47 | $249,039 | 7 | 20th Century Fox International | false | false |
