| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Night at the Museum: Battle of the Smithsonian | $154,817 | -2.5% | 80 | - | $1,935 | $904,912 | 4 | NuMetro Distribution | false | false |
| 2 | 1 | Terminator Salvation | $136,475 | -46.9% | 79 | - | $1,727 | $480,726 | 2 | Ster-Kinekor Pictures | false | false |
| 3 | 5 | Ghosts of Girlfriends Past | $80,548 | +13.7% | 47 | - | $1,713 | $667,410 | 5 | NuMetro Distribution | false | false |
| 4 | - | State of Play | $72,791 | - | 31 | - | $2,348 | $72,791 | 1 | United International Pictures | true | false |
| 5 | - | Drag Me to Hell | $70,031 | - | 40 | - | $1,750 | $70,031 | 1 | NuMetro Distribution | true | false |
| 6 | 3 | Duplicity | $66,783 | -24.4% | 43 | - | $1,553 | $373,940 | 3 | United International Pictures | false | false |
| 7 | 4 | Angels & Demons | $62,286 | -14.9% | 71 | -5 | $877 | $899,627 | 5 | Ster-Kinekor Pictures | false | false |
| 8 | 8 | 17 Again | $26,345 | -7.2% | 43 | -4 | $612 | $1,195,048 | 9 | NuMetro Distribution | false | false |
| 9 | 6 | X-Men Origins: Wolverine | $22,078 | -39.6% | 41 | -26 | $538 | $1,269,917 | 7 | NuMetro Distribution | false | false |
| 10 | 9 | Hannah Montana: The Movie | $19,143 | -30.2% | 32 | -16 | $598 | $686,098 | 7 | Ster-Kinekor Pictures | false | false |
| 11 | - | Sunshine Cleaning | $16,571 | - | 10 | - | $1,657 | $16,571 | 1 | United International Pictures | true | false |
| 12 | 7 | White Wedding | $15,562 | -47.6% | 23 | -9 | $676 | $579,940 | 7 | Ster-Kinekor Pictures | false | false |
| 13 | 13 | Coraline | $15,191 | +17.1% | 10 | -1 | $1,519 | $169,551 | 6 | United International Pictures | false | false |
| 14 | 10 | Star Trek | $11,525 | -41.1% | 20 | -11 | $576 | $352,115 | 6 | United International Pictures | false | false |
| 15 | 11 | The Burning Plain | $11,513 | -30.4% | 10 | - | $1,151 | $36,689 | 2 | United International Pictures | false | false |
| 16 | - | Adventureland | $10,904 | - | 10 | - | $1,090 | $10,904 | 1 | Ster-Kinekor Pictures | true | false |
| 17 | 12 | The Last House on the Left | $7,471 | -51.7% | 16 | -4 | $466 | $106,174 | 4 | United International Pictures | false | false |
| 18 | 15 | Slumdog Millionaire | $6,499 | -8.4% | 14 | -2 | $464 | $1,212,370 | 15 | Ster-Kinekor Pictures | false | false |
| 19 | 16 | The Uninvited | $6,453 | -5.7% | 8 | -2 | $806 | $33,211 | 3 | United International Pictures | false | false |
| 20 | 19 | The Reader | $4,565 | -13.2% | 7 | -1 | $652 | $321,748 | 12 | Ster-Kinekor Pictures | false | false |
| 21 | 21 | Miss March | $3,277 | -15.1% | 5 | - | $655 | $16,261 | 3 | NuMetro Distribution | false | false |
| 22 | - | Man on Wire | $3,180 | - | 3 | - | $1,060 | $3,180 | 5 | Ster-Kinekor Pictures | false | false |
| 23 | 22 | Gran Torino | $1,286 | +6.4% | 2 | -1 | $643 | $295,574 | 12 | NuMetro Distribution | false | false |
| 24 | 23 | Street Fighter: The Legend of Chun-Li | $1,205 | +28.7% | 5 | -2 | $241 | $69,699 | 6 | NuMetro Distribution | false | false |
