| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Proposal | $2,818,700 | - | 280 | - | $10,066 | $3,239,489 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | The Hangover | $2,591,322 | -7.3% | 227 | +1 | $11,415 | $6,465,600 | 2 | Warner Bros. | false | false |
| 3 | - | Year One | $1,583,708 | - | 185 | - | $8,560 | $1,583,708 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | Terminator Salvation | $1,060,866 | -43.9% | 344 | -42 | $3,083 | $10,618,542 | 3 | Sony Pictures Releasing | false | false |
| 5 | 3 | Land of the Lost | $743,794 | -40.1% | 219 | - | $3,396 | $2,335,929 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | Night at the Museum: Battle of the Smithsonian | $626,275 | -35.5% | 264 | -54 | $2,372 | $12,397,461 | 5 | 20th Century Fox International | false | false |
| 7 | 6 | State of Play | $370,585 | -36.1% | 203 | -20 | $1,825 | $4,927,060 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | Angels & Demons | $349,094 | -36% | 221 | -69 | $1,579 | $13,944,577 | 6 | Sony Pictures Releasing | false | false |
| 9 | 5 | I Love You, Man | $291,724 | -50.6% | 186 | -1 | $1,568 | $3,297,414 | 3 | Paramount Pictures International | false | false |
| 10 | 8 | Star Trek | $197,025 | -29.4% | 121 | -48 | $1,628 | $12,577,122 | 7 | Paramount Pictures International | false | false |
| 11 | - | Disgrace | $168,444 | - | 24 | - | $7,018 | $168,444 | 1 | Icon Film Distribution | true | false |
| 12 | 10 | Sunshine Cleaning | $130,581 | -18.2% | 55 | - | $2,374 | $411,424 | 2 | Madman Entertainment | false | false |
| 13 | 9 | Samson & Delilah | $118,431 | -29.5% | 38 | - | $3,116 | $1,798,846 | 7 | Paramount Pictures International | false | false |
| 14 | 12 | Is Anybody There? | $61,550 | -24% | 42 | +10 | $1,465 | $395,035 | 3 | Hopscotch Films | false | false |
| 15 | 13 | My Year Without Sex | $60,065 | -23.4% | 23 | -2 | $2,611 | $597,430 | 5 | Paramount Pictures International | false | false |
| 16 | 14 | X-Men Origins: Wolverine | $33,930 | -51.2% | 40 | -46 | $848 | $14,924,362 | 8 | 20th Century Fox International | false | false |
| 17 | 11 | Ghosts of Girlfriends Past | $27,165 | -72.2% | 61 | -35 | $445 | $5,227,478 | 7 | Roadshow Films | false | false |
| 18 | - | Children of Winter | $24,366 | - | 2 | - | $12,183 | $220,214 | 5 | - | false | false |
| 19 | 16 | Under the Sea 3D | $23,175 | -11.5% | 2 | - | $11,587 | $712,969 | 17 | IMAX | false | false |
| 20 | 15 | The Boy in the Striped Pajamas | $22,543 | -39.1% | 32 | -22 | $704 | $2,929,712 | 9 | Walt Disney Pictures | false | false |
| 21 | - | Noodle | $12,655 | - | 4 | - | $3,163 | $12,655 | 1 | Potential Films | true | false |
| 22 | 19 | Gomorrah | $12,113 | -28.4% | 12 | -3 | $1,009 | $363,962 | 6 | Madman Entertainment | false | false |
| 23 | 20 | The Merchant of Venice 2009 Re-release | $10,978 | -20.6% | 8 | +1 | $1,372 | $33,065 | 2 | Arkles Entertainment | false | false |
