| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Hangover | $17,595 | -46.2% | 3 | - | $5,865 | $74,743 | 2 | - | false | false |
| 2 | 2 | Terminator Salvation | $8,937 | -64.6% | 6 | - | $1,489 | $139,868 | 3 | Sony Pictures Releasing | false | false |
| 3 | 5 | Angels & Demons | $5,582 | -54.1% | 7 | - | $797 | $280,442 | 6 | Sony Pictures Releasing | false | false |
| 4 | - | Ultimate Heist | $4,962 | - | 1 | - | $4,962 | $4,962 | 1 | ACME | true | false |
| 5 | 3 | The Tale of Despereaux | $4,875 | -64% | 7 | - | $696 | $72,420 | 4 | - | false | false |
| 6 | - | The Uninvited | $4,086 | - | 3 | - | $1,362 | $4,086 | 1 | - | true | false |
| 7 | 4 | Drag Me to Hell | $3,712 | -71.6% | 2 | - | $1,856 | $26,311 | 2 | ACME | false | false |
| 8 | 6 | Night at the Museum: Battle of the Smithsonian | $2,926 | -65% | 4 | - | $731 | $104,173 | 5 | - | false | false |
| 9 | 7 | 17 Again | $2,633 | -28% | 3 | - | $877 | $90,788 | 7 | - | false | false |
| 10 | 8 | The Great Buck Howard | $1,647 | -42.3% | 1 | - | $1,647 | $13,088 | 3 | ACME | false | false |
| 11 | 9 | Knowing | $1,591 | -42.3% | 2 | - | $795 | $80,586 | 11 | ACME | false | false |
| 12 | 10 | The Boat That Rocked | $1,483 | -43.7% | 3 | - | $494 | $57,412 | 8 | - | false | false |
| 13 | 11 | I Love You, Man | $753 | -63.7% | 3 | - | $251 | $61,860 | 9 | - | false | false |
| 14 | 13 | Observe and Report | $344 | -62.2% | 2 | - | $172 | $14,476 | 4 | - | false | false |
| 15 | 12 | Hannah Montana: The Movie | $186 | -79.6% | 2 | - | $93 | $20,559 | 6 | - | false | false |
