| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Up | $292,383 | - | 76 | - | $3,847 | $292,383 | 1 | Walt Disney Pictures | true | false |
| 2 | 2 | The Hangover | $127,536 | -34% | 45 | - | $2,834 | $564,171 | 2 | Warner Bros. | false | false |
| 3 | 1 | Terminator Salvation | $65,625 | -67.5% | 107 | -3 | $613 | $1,244,222 | 3 | - | false | false |
| 4 | 3 | State of Play | $28,661 | -58.1% | 35 | - | $818 | $122,483 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Night at the Museum: Battle of the Smithsonian | $8,837 | -58% | 44 | -31 | $200 | $779,189 | 5 | Gemini Films | false | false |
| 6 | 5 | Angels & Demons | $6,609 | -57.7% | 37 | -16 | $178 | $1,573,987 | 6 | Sony Pictures Releasing | false | false |
| 7 | 6 | Monsters vs. Aliens | $1,219 | -59.6% | 1 | -3 | $1,219 | $841,498 | 14 | Paramount Pictures International | false | false |
| 8 | 7 | Star Trek | $691 | -72.5% | 4 | -13 | $172 | $408,113 | 7 | Paramount Pictures International | false | false |
| 9 | 11 | Observe and Report | $676 | +29.3% | 5 | - | $135 | $66,533 | 6 | Warner Bros. | false | false |
| 10 | 10 | Coraline | $409 | -22.8% | 2 | -1 | $204 | $203,758 | 8 | Universal Pictures International (UPI) | false | false |
