| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Transformers: Revenge of the Fallen | $674,835 | - | 121 | - | $5,577 | $1,070,045 | 1 | United International Pictures | true | false |
| 2 | 1 | Up | $459,319 | -17.8% | 138 | -27 | $3,328 | $3,962,782 | 4 | Walt Disney Pictures | false | false |
| 3 | 2 | Terminator Salvation | $101,790 | -45.6% | 95 | -17 | $1,071 | $1,684,486 | 4 | Sony Pictures Releasing | false | false |
| 4 | 3 | Night at the Museum: Battle of the Smithsonian | $54,541 | -38% | 59 | -45 | $924 | $1,901,994 | 6 | 20th Century Fox International | false | false |
| 5 | 5 | 17 Again | $42,628 | -32.1% | 27 | -5 | $1,578 | $166,160 | 2 | Cine Colombia | false | false |
| 6 | 4 | Angels & Demons | $34,922 | -54.8% | 31 | -38 | $1,126 | $2,694,245 | 7 | Sony Pictures Releasing | false | false |
| 7 | 7 | Death Defying Acts | $18,541 | -47.9% | 21 | -15 | $882 | $177,228 | 3 | Cine Colombia | false | false |
| 8 | 6 | Transporter 3 | $13,098 | -74.7% | 23 | -20 | $569 | $231,612 | 3 | Cineplex | false | false |
| 9 | 8 | Duplicity | $12,389 | -52.6% | 13 | -11 | $953 | $210,542 | 5 | United International Pictures | false | false |
| 10 | 9 | The Unborn | $10,901 | -52.1% | 12 | -11 | $908 | $451,385 | 8 | United International Pictures | false | false |
| 11 | 10 | The Class | $9,982 | -2.4% | 10 | -2 | $998 | $51,525 | 3 | - | false | false |
| 12 | 11 | Summer Hours | $4,388 | -34.4% | 4 | -2 | $1,097 | $16,000 | 2 | Cineplex | false | false |
| 13 | 15 | Venus 2009 Re-release | $2,113 | +2.6% | 3 | - | $704 | $55,883 | 6 | Cine Colombia | false | false |
| 14 | 12 | X-Men Origins: Wolverine | $1,545 | -73.7% | 4 | - | $386 | $1,634,918 | 9 | 20th Century Fox International | false | false |
| 15 | 16 | Frozen River | $1,382 | -22.4% | 3 | - | $460 | $30,495 | 6 | Sony Pictures Releasing | false | false |
| 16 | 19 | Happy-Go-Lucky | $837 | +9.1% | 1 | - | $837 | $22,035 | 5 | Cineplex | false | false |
| 17 | 20 | Star Trek | $626 | -13.4% | 1 | -1 | $626 | $278,919 | 8 | United International Pictures | false | false |
