| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Transformers: Revenge of the Fallen | $68,514 | - | 7 | - | $9,787 | $72,870 | 1 | United International Pictures | true | false |
| 2 | 1 | Omar & Salma | $37,843 | -48.9% | 8 | - | $4,730 | $314,123 | 3 | N/A | false | false |
| 3 | 2 | The Proposal | $31,643 | +7.9% | 6 | - | $5,273 | $85,287 | 2 | Walt Disney Pictures | false | false |
| 4 | 3 | Up | $23,013 | +1.8% | 6 | - | $3,835 | $92,400 | 3 | Walt Disney Pictures | false | false |
| 5 | - | Dukan Shehata | $11,491 | - | 5 | - | $2,298 | $11,491 | 1 | N/A | true | false |
| 6 | - | My Life in Ruins | $11,364 | - | 5 | - | $2,272 | $11,364 | 1 | Prime Pictures | true | false |
| 7 | 4 | The Taking of Pelham 123 | $8,396 | -17.3% | 6 | - | $1,399 | $53,374 | 3 | Sony Pictures Releasing | false | false |
| 8 | 8 | Two Lovers | $4,771 | +7.5% | 4 | - | $1,192 | $20,956 | 3 | N/A | false | false |
| 9 | 5 | Angels & Demons | $4,151 | -49.2% | 5 | -2 | $830 | $181,581 | 7 | Sony Pictures Releasing | false | false |
| 10 | 7 | The Heir Apparent: Largo Winch | $3,722 | -39.2% | 3 | -1 | $1,240 | $12,803 | 2 | N/A | false | false |
| 11 | 6 | State of Play | $3,720 | -42.4% | 2 | -2 | $1,860 | $67,378 | 5 | United International Pictures | false | false |
| 12 | 13 | Coraline | $3,120 | +43.4% | 1 | - | $3,120 | $52,060 | 7 | United International Pictures | false | false |
| 13 | 10 | Terminator Salvation | $3,117 | -28.8% | 3 | - | $1,039 | $79,421 | 6 | N/A | false | false |
| 14 | 9 | Night at the Museum: Battle of the Smithsonian | $1,628 | -63.1% | 3 | -2 | $542 | $74,343 | 6 | 20th Century Fox International | false | false |
| 15 | 14 | I Love You, Man | $883 | -54.3% | 1 | -2 | $883 | $70,374 | 5 | United International Pictures | false | false |
| 16 | 17 | Knowing | $759 | +8.9% | 1 | - | $759 | $114,949 | 11 | Jaguar Film International Distribution | false | false |
| 17 | 11 | Make It Happen | $588 | -85.6% | 2 | -2 | $294 | $6,723 | 2 | N/A | false | false |
| 18 | 18 | Defiance | $582 | +65.3% | 2 | - | $291 | $26,662 | 7 | N/A | false | false |
| 19 | 15 | Franklyn | $559 | -62.4% | 3 | -2 | $186 | $3,404 | 2 | Italian International Film | false | false |
| 20 | 22 | New in Town | $355 | +138.3% | 2 | - | $177 | $17,561 | 6 | N/A | false | false |
| 21 | 12 | Crank: High Voltage | $355 | -90.4% | 1 | -3 | $355 | $11,423 | 3 | N/A | false | false |
| 22 | 20 | Hannah Montana: The Movie | $240 | +31.1% | 1 | - | $240 | $125,740 | 12 | Walt Disney Pictures | false | false |
| 23 | 16 | Towelhead | $198 | -79.2% | 1 | - | $198 | $1,589 | 2 | Prime Pictures | false | false |
| 24 | 24 | Charbel | $107 | - | 1 | - | $107 | $314,871 | 21 | Italian International Film | false | false |
| 25 | 21 | It's Alive | $80 | -50.9% | 1 | - | $80 | $23,141 | 10 | Italian International Film | false | false |
| 26 | 25 | Finding Amanda | $27 | -71.9% | 1 | - | $27 | $7,862 | 5 | Italian International Film | false | false |
