| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ice Age: Dawn of the Dinosaurs | $50,419 | - | 12 | - | $4,201 | $71,185 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Transformers: Revenge of the Fallen | $26,256 | -46% | 8 | - | $3,282 | $160,736 | 2 | United International Pictures | false | false |
| 3 | 2 | The Hangover | $20,192 | -18.3% | 5 | - | $4,038 | $328,222 | 4 | Warner Bros. | false | false |
| 4 | 3 | Year One | $3,533 | -54% | 6 | - | $588 | $57,129 | 3 | Sony Pictures Releasing | false | false |
| 5 | 4 | Ghosts of Girlfriends Past | $2,624 | +10.6% | 3 | -1 | $874 | $48,518 | 4 | N/A | false | false |
| 6 | 5 | Tyson | $1,313 | -15.7% | 1 | - | $1,313 | $5,837 | 2 | N/A | false | false |
| 7 | 8 | Terminator Salvation | $869 | -36.8% | 3 | - | $289 | $126,466 | 5 | Sony Pictures Releasing | false | false |
| 8 | 7 | Unstable Fables: The Goldilocks and the 3 Bears Show | $583 | -59.2% | 4 | - | $145 | $8,821 | 4 | N/A | false | false |
| 9 | 6 | Angels & Demons | $548 | -64.3% | 1 | -2 | $548 | $282,563 | 8 | Sony Pictures Releasing | false | false |
| 10 | 12 | Coraline | $473 | -40.1% | 1 | - | $473 | $26,909 | 6 | United International Pictures | false | false |
| 11 | 10 | Vampire Killers | $392 | -54.4% | 1 | -1 | $392 | $2,302 | 2 | N/A | false | false |
| 12 | 14 | Hannah Montana: The Movie | $382 | -6.1% | 2 | +1 | $191 | $28,824 | 8 | Walt Disney Pictures | false | false |
| 13 | 15 | Star Trek | $343 | +75.9% | 1 | - | $343 | $101,352 | 9 | United International Pictures | false | false |
| 14 | 13 | Management | $231 | -64.8% | 1 | -1 | $231 | $17,631 | 5 | N/A | false | false |
| 15 | 11 | The True Story of Puss'N Boots | $161 | -80.9% | 1 | -1 | $161 | $37,133 | 10 | N/A | false | false |
| 16 | 9 | Night at the Museum: Battle of the Smithsonian | $150 | -84.9% | 1 | -1 | $150 | $92,573 | 7 | 20th Century Fox International | false | false |
