| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ice Age: Dawn of the Dinosaurs | $176,179 | - | 14 | - | $12,584 | $378,772 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Transformers: Revenge of the Fallen | $15,017 | -68.2% | 9 | -1 | $1,668 | $148,907 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 3 | The Hangover | $10,754 | -43.7% | 7 | - | $1,536 | $207,055 | 4 | - | false | false |
| 4 | 2 | The Proposal | $8,635 | -55% | 7 | - | $1,233 | $103,769 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 5 | Terminator Salvation | $1,330 | -62.4% | 5 | -4 | $266 | $172,821 | 5 | Sony Pictures Releasing | false | false |
| 6 | 4 | Drag Me to Hell | $1,244 | -74% | 5 | - | $248 | $65,058 | 4 | ACME | false | false |
| 7 | 8 | State of Play | $1,099 | -38.1% | 1 | - | $1,099 | $6,272 | 3 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | Ultimate Heist | $1,005 | -64.8% | 2 | - | $502 | $5,851 | 2 | ACME | false | false |
| 9 | 7 | Angels & Demons | $652 | -65.4% | 5 | - | $130 | $292,537 | 8 | Sony Pictures Releasing | false | false |
| 10 | 9 | Night at the Museum: Battle of the Smithsonian | $492 | -66.3% | 3 | -4 | $164 | $101,982 | 7 | Universal Pictures International (UPI) | false | false |
| 11 | 15 | Ghosts of Girlfriends Past | $304 | -38% | 1 | -1 | $304 | $65,146 | 6 | - | false | false |
| 12 | 11 | Fighting | $197 | -82.7% | 3 | -1 | $65 | $77,955 | 6 | Universal Pictures International (UPI) | false | false |
| 13 | 10 | Monsters vs. Aliens | $134 | -90.5% | 3 | -2 | $44 | $223,211 | 14 | Universal Pictures International (UPI) | false | false |
| 14 | - | The Uninvited | $120 | - | 1 | - | $120 | $20,596 | 7 | Universal Pictures International (UPI) | false | false |
| 15 | 19 | 17 Again | $117 | +85.7% | 1 | - | $117 | $131,445 | 9 | - | false | false |
| 16 | - | WALL·E | $77 | - | 1 | - | $77 | $448,220 | 51 | Universal Pictures International (UPI) | false | false |
| 17 | 13 | Coraline | $74 | -87.5% | 1 | -1 | $74 | $49,271 | 9 | Universal Pictures International (UPI) | false | false |
| 18 | 20 | Star Trek | $47 | -21.7% | 1 | - | $47 | $24,885 | 9 | Universal Pictures International (UPI) | false | false |
| 19 | 18 | Hotel for Dogs | $40 | -54.5% | 1 | - | $40 | $49,851 | 16 | Universal Pictures International (UPI) | false | false |
| 20 | 26 | Bolt | $35 | +250% | 1 | - | $35 | $327,808 | 19 | Universal Pictures International (UPI) | false | false |
| 21 | - | Newsmakers | $24 | - | 1 | - | $24 | $7,338 | 9 | N/A | false | false |
| 22 | 16 | Jonas Brothers: The 3D Concert Experience | $17 | -92.3% | 1 | -1 | $17 | $4,820 | 4 | Universal Pictures International (UPI) | false | false |
| 23 | 17 | The Tale of Despereaux | $14 | -90% | 1 | -2 | $14 | $282,007 | 28 | Universal Pictures International (UPI) | false | false |
