| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ice Age: Dawn of the Dinosaurs | $197,977 | - | 12 | - | $16,498 | $197,977 | 1 | - | true | false |
| 2 | 1 | Transformers: Revenge of the Fallen | $11,592 | -78.6% | 5 | - | $2,318 | $85,885 | 2 | - | false | false |
| 3 | - | Ghosts of Girlfriends Past | $10,204 | - | 2 | - | $5,102 | $10,204 | 1 | - | true | false |
| 4 | 2 | The Hangover | $8,794 | -50% | 3 | - | $2,931 | $119,267 | 4 | - | false | false |
| 5 | 5 | Ultimate Heist | $2,369 | -44.7% | 1 | - | $2,369 | $16,008 | 3 | ACME | false | false |
| 6 | 4 | Terminator Salvation | $2,316 | -53.6% | 6 | - | $386 | $153,827 | 5 | Sony Pictures Releasing | false | false |
| 7 | 3 | Angels & Demons | $2,039 | -62.1% | 7 | - | $291 | $292,905 | 8 | Sony Pictures Releasing | false | false |
| 8 | - | OSS 117: Lost in Rio | $1,871 | - | 1 | - | $1,871 | $1,871 | 1 | ACME | true | false |
| 9 | 8 | Drag Me to Hell | $1,423 | -60.9% | 2 | - | $711 | $36,362 | 4 | ACME | false | false |
| 10 | 9 | The Uninvited | $1,242 | -62.3% | 3 | - | $414 | $13,005 | 3 | - | false | false |
| 11 | 6 | Night at the Museum: Battle of the Smithsonian | $549 | -85.9% | 4 | - | $137 | $112,135 | 7 | - | false | false |
| 12 | 7 | The Tale of Despereaux | $351 | -91% | 7 | - | $50 | $79,979 | 6 | - | false | false |
