| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Transformers: Revenge of the Fallen | $800,109 | -37.2% | 18 | - | $44,450 | $4,992,706 | 2 | United International Pictures | false | false |
| 2 | - | Ice Age: Dawn of the Dinosaurs | $411,224 | - | 16 | - | $25,701 | $740,075 | 1 | 20th Century Fox International | true | false |
| 3 | - | Drag Me to Hell | $86,216 | - | 16 | - | $5,388 | $118,552 | 1 | N/A | true | false |
| 4 | 2 | The Hangover | $19,454 | -51.8% | 12 | -3 | $1,621 | $448,140 | 4 | Warner Bros. | false | false |
| 5 | 8 | Star Trek | $5,751 | +0.7% | 1 | - | $5,751 | $557,031 | 9 | United International Pictures | false | false |
| 6 | - | The Taking of Pelham 123 | $5,707 | - | 9 | - | $634 | $786,158 | - | Sony Pictures Releasing | - | false |
| 7 | 5 | If You Are the One | $4,269 | -59.6% | 5 | - | $853 | $34,671 | 2 | N/A | false | false |
| 8 | 6 | Night at the Museum: Battle of the Smithsonian | $3,886 | -58.8% | 5 | - | $777 | $1,653,058 | 7 | 20th Century Fox International | false | false |
| 9 | - | Grace Is Gone | $3,052 | - | 2 | - | $1,526 | $3,836 | 1 | N/A | true | false |
| 10 | - | Jerichow | $1,788 | - | 1 | - | $1,788 | $2,289 | 1 | N/A | true | false |
| 11 | 9 | Portrait of a Beauty | $1,689 | -52.4% | 2 | -2 | $844 | $11,030 | 2 | N/A | false | false |
| 12 | 4 | Terminator Salvation | $1,646 | -87.5% | 5 | -13 | $329 | $3,389,288 | 6 | Sony Pictures Releasing | false | false |
| 13 | 7 | Angels & Demons | $1,202 | -83.3% | 4 | -6 | $300 | $4,159,630 | 8 | Sony Pictures Releasing | false | false |
| 14 | 13 | I've Loved You So Long | $1,028 | -41% | 1 | - | $1,028 | $21,932 | 4 | N/A | false | false |
| 15 | 12 | O'Horten | $892 | -60.5% | 2 | - | $446 | $12,330 | 112 | N/A | false | false |
| 16 | 11 | La fille de Monaco | $854 | -63.6% | 2 | - | $427 | $15,824 | 3 | N/A | false | false |
| 17 | 15 | One Million Yen Girl | $529 | -62.7% | 1 | - | $529 | $11,633 | 112 | N/A | false | false |
| 18 | 20 | The Lark Farm | $418 | +21.2% | 1 | - | $418 | $11,822 | 10 | N/A | false | false |
| 19 | 17 | Brass Knuckle Boys | $382 | -35.9% | 1 | - | $382 | $61,101 | 5 | N/A | false | false |
| 20 | - | Ong Bak 2 | $258 | - | 1 | - | $258 | $11,058 | 2 | N/A | false | false |
| 21 | 18 | Permanent Residence | $240 | -57.7% | 1 | - | $240 | $33,237 | 4 | N/A | false | false |
