| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: Dawn of the Dinosaurs | $144,242 | -18.1% | 14 | - | $10,303 | $670,433 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | - | Public Enemies | $23,079 | - | 7 | - | $3,297 | $26,930 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 3 | The Hangover | $12,698 | +18.1% | 7 | - | $1,814 | $231,351 | 5 | - | false | false |
| 4 | 2 | Transformers: Revenge of the Fallen | $11,989 | -20.2% | 10 | +1 | $1,198 | $175,595 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | The Proposal | $8,890 | +3% | 7 | - | $1,270 | $122,222 | 4 | Universal Pictures International (UPI) | false | false |
| 6 | - | The Haunting in Connecticut | $8,025 | - | 6 | - | $1,337 | $8,765 | 1 | Universal Pictures International (UPI) | true | false |
| 7 | 7 | State of Play | $424 | -61.4% | 1 | - | $424 | $7,725 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 10 | Night at the Museum: Battle of the Smithsonian | $385 | -21.7% | 3 | - | $128 | $102,587 | 8 | Universal Pictures International (UPI) | false | false |
| 9 | 17 | Coraline | $372 | +402.7% | 1 | - | $372 | $49,817 | 10 | Universal Pictures International (UPI) | false | false |
| 10 | 8 | Ultimate Heist | $369 | -63.3% | 1 | -1 | $369 | $6,943 | 3 | ACME | false | false |
| 11 | 9 | Angels & Demons | $290 | -55.5% | 2 | -3 | $145 | $293,688 | 9 | Sony Pictures Releasing | false | false |
| 12 | 13 | Monsters vs. Aliens | $246 | +83.6% | 2 | -1 | $123 | $223,523 | 15 | Universal Pictures International (UPI) | false | false |
| 13 | 11 | Ghosts of Girlfriends Past | $196 | -35.5% | 2 | +1 | $98 | $65,445 | 7 | - | false | false |
| 14 | - | Madagascar: Escape 2 Africa | $182 | - | 1 | - | $182 | $748,906 | 33 | Universal Pictures International (UPI) | false | false |
| 15 | 5 | Terminator Salvation | $158 | -88.1% | 2 | -3 | $79 | $174,455 | 6 | Sony Pictures Releasing | false | false |
| 16 | 14 | The Uninvited | $113 | -5.8% | 1 | - | $113 | $20,737 | 8 | Universal Pictures International (UPI) | false | false |
| 17 | 15 | 17 Again | $79 | -32.5% | 2 | +1 | $39 | $131,594 | 10 | - | false | false |
| 18 | - | Observe and Report | $29 | - | 1 | - | $29 | $22,897 | 9 | - | false | false |
| 19 | 12 | Fighting | $22 | -88.8% | 1 | -2 | $22 | $78,039 | 7 | Universal Pictures International (UPI) | false | false |
| 20 | 20 | Bolt | $21 | -40% | 1 | - | $21 | $327,499 | 20 | Universal Pictures International (UPI) | false | false |
| 21 | 18 | Star Trek | $14 | -70.2% | 1 | - | $14 | $25,178 | 10 | Universal Pictures International (UPI) | false | false |
