| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: Dawn of the Dinosaurs | $6,255,397 | -31.7% | 970 | - | $6,448 | $22,329,834 | 2 | 20th Century Fox International | false | false |
| 2 | 2 | Transformers: Revenge of the Fallen | $1,191,141 | -46.8% | 475 | - | $2,507 | $16,070,644 | 3 | Paramount Pictures International | false | false |
| 3 | 3 | Public Enemies | $824,260 | -28% | 398 | - | $2,071 | $2,840,050 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | 4 | The Proposal | $398,691 | -33.6% | 315 | -88 | $1,265 | $5,571,685 | 4 | Walt Disney Pictures | false | false |
| 5 | - | All Inclusive | $387,458 | - | 250 | - | $1,549 | $387,458 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | - | The Code | $246,460 | - | 201 | - | $1,226 | $246,460 | 1 | Gussi Films | true | false |
| 7 | 6 | My Sister's Keeper | $197,482 | -28.5% | 161 | -37 | $1,226 | $1,394,698 | 3 | Warner Bros. | false | false |
| 8 | 8 | 17 Again | $161,635 | +6% | 149 | -58 | $1,084 | $2,187,203 | 4 | Gussi Films | false | false |
| 9 | 5 | Night at the Museum: Battle of the Smithsonian | $141,475 | -53.4% | 258 | -155 | $548 | $9,852,318 | 5 | 20th Century Fox International | false | false |
| 10 | 7 | Up | $122,795 | -48.4% | 235 | -146 | $522 | $13,960,311 | 6 | Walt Disney Pictures | false | false |
| 11 | - | Smother | $76,697 | - | 80 | - | $958 | $76,697 | 1 | Videocine | true | false |
| 12 | 17 | Push | $39,087 | +609.5% | 42 | +31 | $930 | $799,796 | 17 | N/A | false | false |
| 13 | - | Gomorrah | $20,038 | - | 9 | - | $2,226 | $20,038 | 1 | N/A | true | false |
| 14 | 11 | State of Play | $14,839 | -20.7% | 28 | +2 | $529 | $1,583,512 | 6 | Universal Pictures International (UPI) | false | false |
| 15 | 15 | Ghosts of Girlfriends Past | $13,449 | +45.6% | 14 | -3 | $960 | $2,750,044 | 9 | Warner Bros. | false | false |
| 16 | - | Religulous | $13,298 | - | 26 | - | $511 | $13,298 | 1 | N/A | true | false |
| 17 | 9 | Angels & Demons | $13,076 | -72.9% | 24 | -61 | $544 | $13,361,171 | 9 | Sony Pictures Releasing | false | false |
| 18 | 10 | Happy-Go-Lucky | $9,948 | -48.1% | 8 | -3 | $1,243 | $75,678 | 3 | N/A | false | false |
| 19 | 13 | Hannah Montana: The Movie | $7,519 | -31.2% | 14 | -14 | $537 | $2,445,474 | 8 | Walt Disney Pictures | false | false |
| 20 | 21 | The Last House on the Left | $7,129 | +134% | 17 | +9 | $419 | $433,403 | 8 | Universal Pictures International (UPI) | false | false |
| 21 | 27 | Personal Effects | $6,282 | +2,539.5% | 7 | +5 | $897 | $88,103 | 7 | Gussi Films | false | false |
| 22 | 23 | Rachel Getting Married | $4,516 | +251.4% | 6 | +3 | $752 | $148,544 | 17 | Sony Pictures Releasing | false | false |
| 23 | 20 | Then She Found Me | $4,279 | +22.6% | 15 | +3 | $285 | $159,322 | 9 | Videocine | false | false |
| 24 | 12 | Star Trek | $3,622 | -78.9% | 17 | -29 | $213 | $3,412,117 | 10 | Paramount Pictures International | false | false |
| 25 | 24 | I'm Gonna Explode | $3,557 | +274.8% | 20 | +19 | $177 | $46,910 | 113 | Videocine | false | false |
| 26 | 18 | Three Monkeys | $3,323 | -18.1% | 1 | -2 | $3,323 | $32,896 | 5 | N/A | false | false |
| 27 | 22 | Sin Nombre | $2,842 | -4% | 9 | +3 | $315 | $610,225 | 9 | Universal Pictures International (UPI) | false | false |
| 28 | 14 | X-Men Origins: Wolverine | $2,496 | -74.2% | 11 | -6 | $226 | $10,263,991 | 11 | 20th Century Fox International | false | false |
| 29 | 16 | Blame it on Fidel | $1,715 | -79.9% | 4 | -2 | $428 | $33,132 | 3 | N/A | false | false |
| 30 | 19 | The Band's Visit | $1,581 | -55.5% | 3 | -7 | $527 | $60,773 | 6 | N/A | false | false |
| 31 | 26 | Earth | $1,545 | +349.1% | 5 | +3 | $309 | $950,290 | 9 | Walt Disney Pictures | false | false |
