| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: Dawn of the Dinosaurs | $2,028,241 | +46.9% | 241 | +1 | $8,415 | $4,871,222 | 2 | 20th Century Fox International | false | false |
| 2 | - | Brüno | $949,596 | - | 93 | - | $10,210 | $953,448 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 2 | Transformers: Revenge of the Fallen | $419,475 | -17.7% | 108 | - | $3,884 | $2,975,001 | 3 | Universal Pictures International (UPI) | false | false |
| 4 | 3 | The Proposal | $388,775 | +42.9% | 84 | - | $4,628 | $2,215,417 | 4 | Walt Disney Pictures | false | false |
| 5 | - | Het geheim van Mega Mindy | $368,230 | - | 107 | - | $3,441 | $516,591 | 1 | Independent Films | true | false |
| 6 | 4 | The Hangover | $337,769 | +26.8% | 67 | - | $5,041 | $3,025,944 | 5 | Warner Bros. | false | false |
| 7 | 6 | Angels & Demons | $151,371 | +29.9% | 73 | -35 | $2,073 | $7,429,148 | 9 | Sony Pictures Releasing | false | false |
| 8 | 5 | Drag Me to Hell | $136,595 | <0.1% | 40 | - | $3,414 | $391,548 | 2 | RCV Film Distribution | false | false |
| 9 | 10 | Coco Before Chanel | $46,282 | +98.5% | 27 | -2 | $1,714 | $782,001 | 7 | RCV Film Distribution | false | false |
| 10 | 9 | Night at the Museum: Battle of the Smithsonian | $33,700 | +26.2% | 47 | -35 | $717 | $2,269,077 | 8 | Warner Bros. | false | false |
| 11 | 8 | State of Play | $30,678 | +14.7% | 22 | -14 | $1,394 | $333,321 | 4 | Universal Pictures International (UPI) | false | false |
| 12 | 12 | Disgrace | $25,713 | +148.1% | 11 | - | $2,337 | $205,298 | 6 | A-Film Distribution | false | false |
| 13 | - | A Summer in Genoa | $25,217 | - | 7 | - | $3,602 | $30,787 | 1 | A-Film Distribution | true | false |
| 14 | 11 | The Reader | $23,447 | +114.6% | 19 | -5 | $1,234 | $1,910,447 | 15 | Benelux Film Distributors | false | false |
| 15 | 17 | Beverly Hills Chihuahua | $21,224 | +245.9% | 51 | -6 | $416 | $984,768 | 12 | Walt Disney Pictures | false | false |
| 16 | - | Management | $21,207 | - | 8 | - | $2,650 | $36,107 | 1 | RCV Film Distribution | true | false |
| 17 | 7 | Terminator Salvation | $20,995 | -37.6% | 16 | -19 | $1,312 | $2,064,601 | 6 | Sony Pictures Releasing | false | false |
| 18 | 15 | Chéri | $14,621 | +78.6% | 18 | - | $812 | $60,317 | 3 | Benelux Film Distributors | false | false |
| 19 | 13 | 17 Again | $14,580 | +61.4% | 18 | -13 | $810 | $2,303,876 | 12 | RCV Film Distribution | false | false |
| 20 | 16 | The Girl on the Train | $13,124 | +95.5% | 11 | - | $1,193 | $67,384 | 4 | Benelux Film Distributors | false | false |
