| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: Dawn of the Dinosaurs | $1,184,775 | -14% | 189 | - | $6,268 | $5,477,555 | 2 | 20th Century Fox International | false | false |
| 2 | - | Brüno | $507,802 | - | 61 | - | $8,324 | $507,802 | 1 | Nordisk Film | true | false |
| 3 | 3 | The Hangover | $207,985 | +16% | 45 | +1 | $4,621 | $1,791,379 | 4 | Sandrew Metronome Distribution Sverige AB | false | false |
| 4 | 2 | Transformers: Revenge of the Fallen | $161,871 | -37.8% | 86 | -16 | $1,882 | $2,123,160 | 3 | United International Pictures | false | false |
| 5 | 5 | Angels & Demons | $48,233 | +25.7% | 21 | -7 | $2,296 | $4,367,853 | 8 | Sony Pictures Releasing | false | false |
| 6 | 4 | My Bloody Valentine | $34,311 | -35.8% | 13 | -4 | $2,639 | $145,626 | 2 | Scanbox Entertainment | false | false |
| 7 | 6 | 17 Again | $24,377 | -17.6% | 20 | -6 | $1,218 | $389,652 | 4 | Svensk Filmindustri (SF) | false | false |
| 8 | 9 | Drag Me to Hell | $22,139 | +53.3% | 19 | +7 | $1,165 | $330,583 | 5 | Scanbox Entertainment | false | false |
| 9 | - | Ghosts of Girlfriends Past | $19,352 | - | 10 | - | $1,935 | $19,352 | - | Svensk Filmindustri (SF) | - | false |
| 10 | 7 | Welcome to the Sticks | $18,989 | -8.6% | 23 | -2 | $825 | $74,931 | 2 | N/A | false | false |
| 11 | 11 | The Girl with the Dragon Tattoo | $12,436 | +48.9% | 6 | -1 | $2,072 | $7,354,027 | 18 | Nordisk Film | false | false |
| 12 | 8 | Terminator Salvation | $11,453 | -26.1% | 27 | -2 | $424 | $1,366,569 | 6 | Sony Pictures Releasing | false | false |
| 13 | - | Fighting | $9,878 | - | 5 | - | $1,975 | $9,878 | 7 | United International Pictures | false | false |
| 14 | 10 | Night at the Museum: Battle of the Smithsonian | $8,030 | -22.3% | 18 | -8 | $446 | $828,668 | 7 | 20th Century Fox International | false | false |
| 15 | 13 | Hannah Montana: The Movie | $6,672 | -14.6% | 11 | -6 | $606 | $2,254,496 | 11 | Walt Disney Pictures | false | false |
| 16 | 15 | Last Chance Harvey | $5,357 | +20.3% | 5 | -1 | $1,071 | $27,831 | 3 | N/A | false | false |
| 17 | 14 | Bob the Builder: Race to the Finish | $5,279 | -1.1% | 9 | +1 | $586 | $111,406 | 5 | Svensk Filmindustri (SF) | false | false |
| 18 | 16 | Duplicity | $4,389 | +10% | 7 | -2 | $627 | $193,356 | 6 | United International Pictures | false | false |
| 19 | 17 | Slumdog Millionaire | $4,124 | +16.5% | 2 | -2 | $2,062 | $2,821,527 | 25 | Svensk Filmindustri (SF) | false | false |
| 20 | 19 | Star Trek | $3,033 | +8.1% | 7 | -3 | $433 | $1,036,013 | 10 | United International Pictures | false | false |
| 21 | 12 | The Haunting in Connecticut | $2,611 | -68.5% | 4 | -6 | $652 | $40,137 | 3 | N/A | false | false |
| 22 | 18 | I Love You, Man | $2,228 | -35.1% | 7 | -5 | $318 | $272,573 | 5 | United International Pictures | false | false |
