| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: Dawn of the Dinosaurs | $1,047,536 | +8.2% | 158 | +24 | $6,629 | $3,773,269 | 3 | 20th Century Fox International | false | false |
| 2 | - | The Taking of Pelham 123 | $265,376 | - | 45 | - | $5,897 | $265,376 | 1 | Sony Pictures Releasing | true | false |
| 3 | 2 | Transformers: Revenge of the Fallen | $204,584 | -16.5% | 117 | +26 | $1,748 | $2,056,003 | 4 | Paramount Pictures International | false | false |
| 4 | 3 | The Proposal | $138,855 | -13.4% | 81 | +14 | $1,714 | $541,514 | 3 | Walt Disney Pictures | false | false |
| 5 | 5 | Up | $83,961 | +44.3% | 129 | +37 | $650 | $3,238,672 | 6 | Walt Disney Pictures | false | false |
| 6 | - | 100% lucha, el amo de los clones | $66,494 | - | 67 | - | $992 | $66,494 | 1 | Primer Plano Film Group | true | false |
| 7 | - | I've Loved You So Long | $58,769 | - | 19 | - | $3,093 | $58,769 | 1 | Alfa Films | true | false |
| 8 | 4 | Solstice | $52,253 | -20.1% | 26 | - | $2,009 | $141,756 | 2 | Distribution Company | false | false |
| 9 | 7 | State of Play | $17,780 | -42.8% | 19 | -5 | $935 | $488,385 | 6 | Universal Pictures International (UPI) | false | false |
| 10 | - | Penelope | $17,741 | - | 22 | - | $806 | $17,741 | 1 | Distribution Company | true | false |
| 11 | 8 | A Christmas Tale | $16,536 | -32.2% | 11 | +1 | $1,503 | $66,293 | 3 | Pachamama Cine | false | false |
| 12 | 10 | Last Chance Harvey | $15,535 | +24.6% | 22 | +2 | $706 | $442,098 | 7 | Distribution Company | false | false |
| 13 | 9 | Pride and Glory | $10,623 | -36.8% | 15 | -5 | $708 | $118,391 | 4 | Distribution Company | false | false |
| 14 | - | Killshot | $8,002 | - | 18 | - | $444 | $51,100 | - | Distribution Company | - | false |
| 15 | 15 | Felicitas | $7,617 | -19.5% | 16 | +1 | $476 | $424,014 | 6 | Pachamama Cine | false | false |
| 16 | 12 | Terminator Salvation | $7,256 | -31.6% | 26 | - | $279 | $1,963,660 | 7 | Sony Pictures Releasing | false | false |
| 17 | - | Katyn | $6,477 | - | 3 | - | $2,159 | $6,477 | 1 | N/A | true | false |
| 18 | 16 | The Unborn | $5,372 | -5% | 19 | +1 | $282 | $770,648 | 9 | Universal Pictures International (UPI) | false | false |
| 19 | 14 | The Visitor | $5,059 | -49.6% | 13 | -1 | $389 | $106,761 | 5 | Impacto Cine | false | false |
| 20 | - | The Secrets | $4,890 | - | 5 | - | $978 | $4,890 | 1 | Distribution Company | true | false |
| 21 | 11 | Happy-Go-Lucky | $3,725 | -69.6% | 8 | -12 | $465 | $126,908 | 5 | N/A | false | false |
| 22 | 13 | Ghosts of Girlfriends Past | $3,480 | -66% | 9 | -17 | $386 | $454,702 | 6 | Distribution Company | false | false |
| 23 | 17 | Angels & Demons | $3,380 | -36.9% | 7 | - | $482 | $3,330,559 | 10 | Sony Pictures Releasing | false | false |
| 24 | 23 | Che: Part Two | $3,094 | +285.8% | 6 | +4 | $515 | $49,298 | 5 | Alfa Films | false | false |
| 25 | 20 | Night at the Museum: Battle of the Smithsonian | $1,794 | -3.4% | 6 | -4 | $299 | $2,553,944 | 9 | 20th Century Fox International | false | false |
| 26 | 21 | Inspector Bellamy | $909 | -33.1% | 4 | - | $227 | $138,495 | 7 | Alfa Films | false | false |
| 27 | 18 | Goodbye Bafana | $586 | -83.9% | 1 | -5 | $586 | $13,383 | 3 | Distribution Company | false | false |
| 28 | 19 | The Zone | $448 | -80.6% | 2 | -2 | $224 | $3,688 | 2 | Primer Plano Film Group | false | false |
| 29 | 24 | 17 Again | $257 | -59.9% | 1 | -1 | $257 | $421,284 | 11 | Distribution Company | false | false |
| 30 | 32 | Star Trek | $256 | +190.9% | 1 | - | $256 | $405,640 | 11 | Paramount Pictures International | false | false |
| 31 | 28 | All the Lonely People | $240 | -42% | 1 | - | $240 | $14,667 | 5 | Primer Plano Film Group | false | false |
| 32 | 30 | The Reader | $174 | -11.2% | 1 | -1 | $174 | $575,227 | 11 | Pachamama Cine | false | false |
| 33 | 31 | Lorna's Silence | $158 | +66.3% | 1 | - | $158 | $91,270 | 10 | Distribution Company | false | false |
| 34 | 34 | Rumba | $47 | +27% | 1 | - | $47 | $67,362 | 16 | Distribution Company | false | false |
| 35 | 29 | The Edge of Heaven | $42 | -80.6% | 1 | - | $42 | $155,456 | 18 | Alfa Films | false | false |
| 36 | 37 | Esperando la carroza 2: Se acabó la fiesta | $28 | - | 1 | - | $28 | $1,287,043 | 16 | Primer Plano Film Group | false | false |
| 37 | 35 | Race to Witch Mountain | $8 | -76.5% | 1 | -1 | $8 | $972,882 | 15 | Walt Disney Pictures | false | false |
