| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Half-Blood Prince | $975,768 | - | 82 | - | $11,899 | $1,106,157 | 1 | Sandrew Metronome Distribution | true | false |
| 2 | 1 | Ice Age: Dawn of the Dinosaurs | $190,696 | -53.4% | 101 | -4 | $1,888 | $2,693,074 | 3 | FS Film Oy | false | false |
| 3 | 2 | Brüno | $124,736 | -49.9% | 35 | - | $3,563 | $609,020 | 2 | Nordisk Film | false | false |
| 4 | 3 | The Hangover | $50,017 | -37.7% | 21 | -10 | $2,381 | $718,578 | 5 | Sandrew Metronome Distribution | false | false |
| 5 | 4 | Transformers: Revenge of the Fallen | $22,794 | -56.8% | 29 | -13 | $786 | $822,630 | 4 | United International Pictures | false | false |
| 6 | 5 | Angels & Demons | $14,986 | -46.2% | 18 | -6 | $832 | $2,223,392 | 10 | Walt Disney Studios Sony Pictures Releasing (WDSSPR) | false | false |
| 7 | 6 | Knowing | $8,019 | -39.7% | 10 | -2 | $801 | $204,219 | 114 | Nordisk Film | false | false |
| 8 | 8 | Terminator Salvation | $5,882 | -42.3% | 7 | -2 | $840 | $834,835 | 7 | Walt Disney Studios Sony Pictures Releasing (WDSSPR) | false | false |
| 9 | 7 | Slumdog Millionaire | $3,803 | -69.7% | 11 | -7 | $345 | $2,091,418 | 19 | FS Film Oy | false | false |
| 10 | 9 | Letters to Father Jacob | $3,461 | -51.7% | 16 | -3 | $216 | $771,817 | 16 | Nordisk Film | false | false |
| 11 | 12 | The Girl with the Dragon Tattoo | $3,177 | -41.1% | 2 | -4 | $1,588 | $894,401 | 17 | Nordisk Film | false | false |
| 12 | 14 | Drag Me to Hell | $2,278 | -55.7% | 6 | -3 | $379 | $144,398 | 6 | Scanbox Entertainment | false | false |
| 13 | 17 | Antichrist | $2,267 | -36.7% | 2 | - | $1,133 | $52,621 | 7 | Nordisk Film | false | false |
| 14 | 10 | 17 Again | $2,247 | -66.3% | 5 | -5 | $449 | $270,414 | 7 | FS Film Oy | false | false |
| 15 | 16 | Anything for Her | $1,786 | -51.8% | 3 | - | $595 | $26,350 | 3 | Cinema Mondo | false | false |
| 16 | 15 | Hannah Montana: The Movie | $1,673 | -65.9% | 7 | -3 | $239 | $464,108 | 12 | Walt Disney Pictures | false | false |
| 17 | 19 | He's Just Not That Into You | $1,545 | -46.7% | 2 | +1 | $772 | $393,100 | 11 | FS Film Oy | false | false |
| 18 | 13 | Night at the Museum: Battle of the Smithsonian | $1,541 | -70.3% | 5 | -6 | $308 | $696,225 | 9 | FS Film Oy | false | false |
| 19 | - | Crossing Over | $1,266 | - | 1 | - | $1,266 | $14,951 | 3 | Nordisk Film | false | false |
| 20 | - | Paris 36 | $1,248 | - | 1 | - | $1,248 | $1,248 | 1 | Walt Disney Studios Sony Pictures Releasing (WDSSPR) | true | false |
