| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: Dawn of the Dinosaurs | $65,331 | -17.7% | 6 | - | $10,888 | $343,051 | 3 | 20th Century Fox International | false | false |
| 2 | 2 | The Hangover | $45,936 | -18.9% | 6 | - | $7,656 | $141,825 | 2 | Warner Bros. | false | false |
| 3 | 3 | Omar & Salma | $38,266 | -6.8% | 9 | +1 | $4,251 | $581,109 | 6 | N/A | false | false |
| 4 | 4 | The Proposal | $24,229 | +2.3% | 6 | - | $4,038 | $224,568 | 5 | Walt Disney Pictures | false | false |
| 5 | 5 | Bobbos | $20,800 | -10.5% | 7 | - | $2,971 | $59,436 | 2 | N/A | false | false |
| 6 | - | 17 Again | $18,878 | - | 3 | - | $6,292 | $18,878 | 1 | N/A | true | false |
| 7 | 6 | Transformers: Revenge of the Fallen | $15,110 | -31.4% | 6 | -1 | $2,518 | $219,954 | 4 | United International Pictures | false | false |
| 8 | - | Red Cliff | $8,354 | - | 5 | - | $1,670 | $8,354 | 1 | Jaguar Film International Distribution | true | false |
| 9 | - | The Criminal | $6,322 | - | 3 | - | $2,107 | $6,322 | 1 | N/A | true | false |
| 10 | 7 | Up | $5,406 | -31% | 5 | -1 | $1,081 | $158,325 | 6 | Walt Disney Pictures | false | false |
| 11 | 11 | My Life in Ruins | $3,805 | -3.2% | 1 | - | $3,805 | $38,829 | 4 | Prime Pictures | false | false |
| 12 | - | Arn: The Knight Templar | $3,764 | - | 6 | - | $627 | $3,764 | 1 | Italian International Film | true | false |
| 13 | - | Newcastle | $3,002 | - | 3 | - | $1,000 | $3,002 | 1 | Prime Pictures | true | false |
| 14 | - | The Boat That Rocked | $2,553 | - | 2 | - | $1,276 | $2,553 | 1 | United International Pictures | true | false |
| 15 | 8 | I Hate Valentine's Day | $1,883 | -76% | 1 | -4 | $1,883 | $36,976 | 3 | Jaguar Film International Distribution | false | false |
| 16 | 18 | Terminator Salvation | $1,624 | +64.2% | 1 | - | $1,624 | $88,551 | 9 | N/A | false | false |
| 17 | 10 | Dukan Shehata | $1,441 | -67.7% | 2 | -2 | $720 | $41,659 | 4 | N/A | false | false |
| 18 | 9 | The Last House on the Left | $1,428 | -70% | 1 | -1 | $1,428 | $21,797 | 3 | N/A | false | false |
| 19 | 16 | I Love You, Man | $885 | -21.1% | 1 | - | $885 | $75,374 | 8 | United International Pictures | false | false |
| 20 | 15 | Obsessed | $712 | -54.4% | 2 | -1 | $356 | $16,715 | 3 | Sony Pictures Releasing | false | false |
| 21 | 20 | Defiance | $588 | -21.6% | 2 | - | $294 | $29,917 | 10 | N/A | false | false |
| 22 | 21 | Two Lovers | $556 | -6.2% | 2 | - | $278 | $30,813 | 6 | N/A | false | false |
| 23 | 12 | The Taking of Pelham 123 | $299 | -92.1% | 1 | -1 | $299 | $73,399 | 6 | Sony Pictures Releasing | false | false |
| 24 | 17 | Angels & Demons | $253 | -75.9% | 1 | -1 | $253 | $188,762 | 10 | Sony Pictures Releasing | false | false |
| 25 | 23 | Hannah Montana: The Movie | $145 | -45.3% | 1 | - | $145 | $133,756 | 15 | Walt Disney Pictures | false | false |
| 26 | 22 | Franklyn | $126 | -74.2% | 1 | -2 | $126 | $5,580 | 5 | Italian International Film | false | false |
| 27 | 24 | It's Alive | $88 | -66.4% | 1 | - | $88 | $24,261 | 13 | Italian International Film | false | false |
| 28 | 25 | Make It Happen | $63 | -50% | 1 | - | $63 | $8,481 | 5 | N/A | false | false |
