| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | G-Force | $509,554 | - | 137 | - | $3,719 | $509,554 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Ice Age: Dawn of the Dinosaurs | $316,727 | -44.3% | 130 | -21 | $2,436 | $7,188,430 | 5 | 20th Century Fox International | false | false |
| 3 | 2 | Harry Potter and the Half-Blood Prince | $199,003 | -46.9% | 134 | -41 | $1,485 | $2,545,224 | 3 | Warner Bros. | false | false |
| 4 | 3 | The Proposal | $68,602 | -21.7% | 40 | -2 | $1,715 | $619,705 | 4 | Walt Disney Pictures | false | false |
| 5 | - | State of Play | $56,104 | - | 30 | - | $1,870 | $56,104 | 1 | United International Pictures | true | false |
| 6 | - | The Bank Job | $51,122 | - | 34 | - | $1,503 | $51,122 | 1 | Cine Colombia | true | false |
| 7 | 4 | He's Just Not That Into You | $33,147 | -46.8% | 30 | -12 | $1,104 | $130,921 | 2 | Cine Colombia | false | false |
| 8 | 5 | Transformers: Revenge of the Fallen | $30,895 | -41.2% | 30 | -27 | $1,029 | $2,896,780 | 6 | United International Pictures | false | false |
| 9 | - | The Edge of Heaven | $12,668 | - | 9 | - | $1,407 | $12,668 | 1 | Cine Colombia | true | false |
| 10 | 8 | The Last House on the Left | $12,021 | -16.6% | 20 | -1 | $601 | $119,474 | 4 | United International Pictures | false | false |
| 11 | 7 | The Wrestler | $9,622 | -57.4% | 11 | -2 | $874 | $45,050 | 2 | Cine Colombia | false | false |
| 12 | 9 | Elegy | $6,913 | -40.8% | 8 | +1 | $864 | $75,254 | 4 | Cine Colombia | false | false |
| 13 | 12 | 17 Again | $6,614 | +34.1% | 10 | +2 | $661 | $288,691 | 7 | Cine Colombia | false | false |
| 14 | 11 | Lemon Tree | $3,752 | -31.5% | 5 | - | $750 | $48,921 | 4 | Cineplex | false | false |
| 15 | 10 | Up | $3,659 | -67.8% | 12 | -16 | $304 | $5,111,251 | 9 | Walt Disney Pictures | false | false |
| 16 | 13 | Night at the Museum: Battle of the Smithsonian | $2,406 | -28.9% | 3 | -1 | $802 | $2,090,687 | 11 | 20th Century Fox International | false | false |
| 17 | 6 | I Love You, Man | $1,752 | -94.9% | 9 | -26 | $194 | $56,825 | 15 | United International Pictures | false | false |
| 18 | 14 | The Class | $1,166 | -39.5% | 2 | -3 | $583 | $90,596 | 8 | - | false | false |
| 19 | 18 | Angels & Demons | $603 | +3.6% | 1 | - | $603 | $2,761,936 | 12 | Sony Pictures Releasing | false | false |
| 20 | 15 | Transporter 3 | $592 | -69.2% | 2 | -1 | $296 | $286,542 | 8 | Cineplex | false | false |
