| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | G-Force | $212,834 | - | 65 | - | $3,274 | $212,834 | 1 | Ster-Kinekor Pictures | true | false |
| 2 | 2 | The Proposal | $159,522 | -22.4% | 65 | - | $2,454 | $1,544,542 | 4 | Ster-Kinekor Pictures | false | false |
| 3 | 1 | Harry Potter and the Half-Blood Prince | $139,542 | -42.4% | 85 | -2 | $1,641 | $1,395,922 | 3 | NuMetro Distribution | false | false |
| 4 | 3 | Ice Age: Dawn of the Dinosaurs | $108,795 | -41% | 82 | -7 | $1,326 | $3,010,592 | 5 | NuMetro Distribution | false | false |
| 5 | 4 | The Hangover | $79,880 | -8.4% | 54 | -1 | $1,479 | $1,522,895 | 7 | NuMetro Distribution | false | false |
| 6 | - | My Life in Ruins | $77,966 | - | 35 | - | $2,227 | $77,966 | 1 | Ster-Kinekor Pictures | true | false |
| 7 | 5 | Transformers: Revenge of the Fallen | $49,036 | -37.8% | 56 | -22 | $875 | $2,276,803 | 6 | United International Pictures | false | false |
| 8 | 6 | Fighting | $44,774 | -23.2% | 30 | - | $1,492 | $128,420 | 2 | United International Pictures | false | false |
| 9 | 7 | Knowing | $34,214 | -23.5% | 48 | -15 | $712 | $735,561 | 5 | United International Pictures | false | false |
| 10 | - | Love Aaj Kal | $31,756 | - | 7 | - | $4,536 | $31,756 | 1 | NuMetro Distribution | true | false |
| 11 | 8 | Brüno | $25,622 | -35.1% | 34 | -4 | $753 | $359,156 | 4 | United International Pictures | false | false |
| 12 | 11 | I Love You, Beth Cooper | $12,370 | -4.1% | 10 | - | $1,237 | $30,504 | 2 | NuMetro Distribution | false | false |
| 13 | 10 | Management | $10,654 | -38.3% | 10 | - | $1,065 | $37,763 | 2 | NuMetro Distribution | false | false |
| 14 | 12 | Obsessed | $10,023 | -0.4% | 14 | -1 | $715 | $295,297 | 7 | Ster-Kinekor Pictures | false | false |
| 15 | 9 | The Haunting in Connecticut | $9,517 | -51.5% | 13 | -12 | $732 | $84,235 | 3 | NuMetro Distribution | false | false |
| 16 | 14 | Crossing Over | $7,885 | -18% | 9 | -1 | $876 | $46,226 | 3 | Ster-Kinekor Pictures | false | false |
| 17 | - | The Young Victoria | $6,401 | - | 9 | - | $711 | $111,940 | 6 | NuMetro Distribution | false | false |
| 18 | - | Heaven on Earth | $5,321 | - | 5 | - | $1,064 | $5,321 | 1 | Ster-Kinekor Pictures | true | false |
| 19 | 17 | Welcome to the Sticks | $3,721 | +3.6% | 4 | - | $930 | $49,025 | 6 | Ster-Kinekor Pictures | false | false |
| 20 | 19 | The Brothers Bloom | $3,373 | +7% | 6 | -1 | $562 | $53,808 | 5 | Ster-Kinekor Pictures | false | false |
| 21 | 15 | State of Play | $3,100 | -32% | 10 | +1 | $310 | $341,362 | 8 | United International Pictures | false | false |
| 22 | 16 | The Song of Sparrows | $2,728 | -26% | 3 | - | $909 | $25,373 | 4 | Ster-Kinekor Pictures | false | false |
| 23 | 20 | The Burning Plain | $1,427 | -41.9% | 5 | -3 | $285 | $93,234 | 9 | United International Pictures | false | false |
| 24 | 23 | Sunshine Cleaning | $683 | -46.4% | 2 | -1 | $341 | $90,432 | 8 | United International Pictures | false | false |
