| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Harry Potter and the Half-Blood Prince | $375,212 | -17.3% | 153 | -17 | $2,452 | $7,910,389 | 5 | Warner Bros. | false | false |
| 2 | 3 | Ice Age: Dawn of the Dinosaurs | $326,279 | +4% | 105 | -24 | $3,107 | $7,844,132 | 7 | 20th Century Fox International | false | false |
| 3 | 1 | G.I. Joe: The Rise of Cobra | $322,654 | -32.9% | 53 | +3 | $6,087 | $936,034 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | 4 | G-Force | $282,917 | +2.5% | 76 | - | $3,722 | $1,400,652 | 3 | Walt Disney Pictures | false | false |
| 5 | 5 | Public Enemies | $207,916 | +1.8% | 53 | - | $3,922 | $1,791,588 | 4 | Universal Pictures International (UPI) | false | false |
| 6 | 6 | The Taking of Pelham 123 | $177,271 | -9.6% | 45 | - | $3,939 | $929,001 | 3 | Sony Pictures Releasing | false | false |
| 7 | - | Bandslam | $124,224 | - | 40 | - | $3,105 | $124,684 | 1 | Belga Films | true | false |
| 8 | 7 | The Proposal | $80,804 | -8.7% | 38 | -2 | $2,126 | $2,522,095 | 9 | Walt Disney Pictures | false | false |
| 9 | 9 | Luke and Lucy: The Texas Rangers | $75,242 | +31.4% | 48 | -4 | $1,567 | $538,644 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 10 | 10 | Het geheim van Mega Mindy | $72,577 | +34% | 33 | - | $2,199 | $1,344,220 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 11 | - | Partir | $71,482 | - | 17 | - | $4,204 | $76,099 | 1 | Benelux Film Distributors | true | false |
| 12 | 8 | Brüno | $69,624 | -18.2% | 35 | -4 | $1,989 | $2,177,289 | 6 | Universal Pictures International (UPI) | false | false |
| 13 | 11 | The Hangover | $41,071 | -21.6% | 10 | -22 | $4,107 | $1,755,359 | 9 | Warner Bros. | false | false |
| 14 | 13 | The Hedgehog | $33,911 | -28.5% | 12 | - | $2,825 | $82,752 | 2 | Cinéart | false | false |
| 15 | 15 | Transformers: Revenge of the Fallen | $28,133 | -30.5% | 26 | -14 | $1,082 | $2,942,790 | 8 | Universal Pictures International (UPI) | false | false |
| 16 | 12 | I Love You, Man | $27,882 | -43% | 14 | -6 | $1,991 | $280,884 | 3 | Universal Pictures International (UPI) | false | false |
| 17 | - | Year One | $24,926 | - | 5 | - | $4,985 | $24,926 | 1 | Sony Pictures Releasing | true | false |
| 18 | 16 | Hannah Montana: The Movie | $23,332 | -5.1% | 30 | -2 | $777 | $590,987 | 6 | Walt Disney Pictures | false | false |
| 19 | - | Amreeka | $16,404 | - | 10 | - | $1,640 | $16,404 | 1 | Cinéart | true | false |
| 20 | - | Park Benches | $15,133 | - | 10 | - | $1,513 | $17,736 | 1 | N/A | true | false |
| 21 | 19 | Angels & Demons | $13,979 | -2% | 6 | -1 | $2,329 | $4,636,991 | 14 | Sony Pictures Releasing | false | false |
| 22 | 21 | Passengers | $11,199 | -5.1% | 6 | - | $1,866 | $65,241 | 3 | Paradiso Entertainment | false | false |
| 23 | 25 | Princess Lillifee | $10,642 | +22% | 13 | -1 | $818 | $39,568 | 21 | Walt Disney Pictures | false | false |
| 24 | 18 | Ghosts of Girlfriends Past | $10,598 | -26.7% | 6 | -5 | $1,766 | $561,881 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 25 | 17 | The Brothers Bloom | $10,144 | -39.9% | 6 | -2 | $1,690 | $36,537 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 26 | 26 | Coraline | $9,580 | +12.1% | 14 | -2 | $684 | $478,753 | 10 | Universal Pictures International (UPI) | false | false |
| 27 | 20 | Drag Me to Hell | $8,978 | -25.5% | 6 | -6 | $1,496 | $587,754 | 8 | Belga Films | false | false |
| 28 | 24 | Broken Embraces | $6,620 | -28.7% | 14 | -1 | $472 | $669,676 | 13 | Alternative Films | false | false |
| 29 | 23 | Fighting | $6,281 | -36.6% | 4 | -3 | $1,570 | $231,640 | 5 | Universal Pictures International (UPI) | false | false |
| 30 | 28 | State of Play | $4,618 | -17.3% | 8 | - | $577 | $554,417 | 9 | Universal Pictures International (UPI) | false | false |
| 31 | 22 | Blame It on Mum | $4,040 | -60.5% | 11 | - | $367 | $96,748 | 4 | Cinéart | false | false |
| 32 | 29 | Kabuli Kid | $3,174 | -35.3% | 4 | - | $793 | $20,137 | 3 | N/A | false | false |
| 33 | 31 | Towelhead | $2,619 | -41.3% | 9 | - | $291 | $29,830 | 3 | Benelux Film Distributors | false | false |
| 34 | 27 | Alternate Weeks (and Half the Vacation) | $2,044 | -64.1% | 5 | -1 | $408 | $50,138 | 3 | Les Films de l'Elysée | false | false |
| 35 | 34 | The Girl with the Dragon Tattoo | $2,022 | -31.3% | 4 | -1 | $505 | $579,790 | 13 | Benelux Film Distributors | false | false |
| 36 | - | Silent Wedding | $2,003 | - | 3 | - | $667 | $2,388 | 1 | Paradiso Entertainment | true | false |
| 37 | - | Donkey Punch | $1,901 | - | 6 | - | $316 | $1,901 | 1 | N/A | true | false |
| 38 | 33 | Disgrace | $1,884 | -40.7% | 4 | -1 | $471 | $25,682 | 4 | A-Film Distribution | false | false |
| 39 | - | High Lane | $1,519 | - | 2 | - | $759 | $72,583 | 6 | Benelux Film Distributors | false | false |
| 40 | - | So Woman! | $1,052 | - | 4 | - | $263 | $3,207 | 1 | N/A | true | false |
| 41 | 39 | The French Kissers | $735 | -14.1% | 3 | -3 | $245 | $283,672 | 8 | Alternative Films | false | false |
| 42 | 30 | Mid-August Lunch | $724 | -83.9% | 5 | -1 | $144 | $119,340 | 10 | ABC Distribution | false | false |
| 43 | - | I Am from Titov Veles | $722 | - | 2 | - | $361 | $1,215 | 1 | N/A | true | false |
| 44 | 42 | The Reader | $481 | +52.2% | 1 | - | $481 | $912,785 | 24 | Benelux Film Distributors | false | false |
| 45 | - | The Good Life | $102 | - | 1 | - | $102 | $102 | 1 | A-Film Distribution | true | false |
