| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | G.I. Joe: The Rise of Cobra | $242,543 | - | 80 | - | $3,031 | $242,543 | 1 | Paramount Pictures International | true | false |
| 2 | 1 | Ghosts of Girlfriends Past | $93,089 | -36% | 43 | - | $2,164 | $299,125 | 2 | Warner Bros. | false | false |
| 3 | 3 | Harry Potter and the Half-Blood Prince | $67,085 | -42.9% | 88 | -3 | $762 | $1,737,064 | 4 | Warner Bros. | false | false |
| 4 | 2 | Public Enemies | $58,121 | -50.9% | 56 | -1 | $1,037 | $640,219 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 5 | The Proposal | $33,818 | -28% | 58 | -2 | $583 | $920,560 | 5 | Walt Disney Pictures | false | false |
| 6 | 4 | Ice Age: Dawn of the Dinosaurs | $30,864 | -39.8% | 62 | -23 | $497 | $2,818,206 | 6 | 20th Century Fox International | false | false |
| 7 | 6 | The Hangover | $5,958 | -24.9% | 5 | -1 | $1,191 | $866,879 | 9 | Warner Bros. | false | false |
| 8 | 9 | Up | $2,944 | -17.2% | 9 | -3 | $327 | $627,206 | 8 | Walt Disney Pictures | false | false |
| 9 | 7 | Fighting | $1,761 | -73.9% | 14 | -13 | $125 | $100,218 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | 8 | Transformers: Revenge of the Fallen | $1,120 | -75.7% | 9 | -18 | $124 | $1,527,038 | 7 | Paramount Pictures International | false | false |
| 11 | 10 | State of Play | $320 | -59.2% | 3 | -1 | $106 | $153,956 | 9 | Universal Pictures International (UPI) | false | false |
