| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Drag Me to Hell | $284,425 | - | 20 | - | $14,221 | $384,859 | 1 | Gulf Film | true | false |
| 2 | 1 | G.I. Joe: The Rise of Cobra | $203,472 | -61.8% | 22 | -8 | $9,248 | $986,994 | 2 | United International Pictures | false | false |
| 3 | - | Funny People | $152,315 | - | 20 | - | $7,615 | $204,703 | 1 | United International Pictures | true | false |
| 4 | 2 | The Hangover | $71,246 | -47.3% | 7 | -4 | $10,178 | $781,897 | 3 | Warner Bros. | false | false |
| 5 | - | My Sister's Keeper | $57,480 | - | 12 | - | $4,790 | $87,521 | 1 | Warner Bros. | true | false |
| 6 | 4 | 1000 Congratulations | $43,292 | -53.5% | 12 | -4 | $3,607 | $1,003,716 | 4 | Gulf Film | false | false |
| 7 | 6 | Ice Age: Dawn of the Dinosaurs | $33,866 | -15.1% | 3 | - | $11,288 | $1,362,738 | 7 | 20th Century Fox International | false | false |
| 8 | - | My Life in Ruins | $33,401 | - | 12 | - | $2,783 | $48,076 | 1 | N/A | true | false |
| 9 | 9 | G-Force | $30,722 | -15.5% | 4 | -3 | $7,680 | $424,206 | 4 | Walt Disney Pictures | false | false |
| 10 | 3 | Orphan | $20,848 | -83% | 9 | -10 | $2,316 | $211,253 | 2 | Warner Bros. | false | false |
| 11 | - | My Best Friend's Girl | $16,284 | - | 9 | - | $1,809 | $102,434 | 2 | Gulf Film | false | false |
| 12 | 11 | Harry Potter and the Half-Blood Prince | $14,435 | -46.3% | 1 | -4 | $14,435 | $1,418,820 | 5 | Warner Bros. | false | false |
| 13 | - | Two Lovers | $14,236 | - | 11 | - | $1,294 | $21,002 | 1 | Gulf Film | true | false |
| 14 | 5 | Imagine That | $13,713 | -72.7% | 12 | -6 | $1,142 | $306,169 | 3 | United International Pictures | false | false |
| 15 | 10 | Fighting | $6,572 | -81.1% | 4 | -15 | $1,643 | $275,665 | 3 | Gulf Film | false | false |
| 16 | 14 | Transformers: Revenge of the Fallen | $5,291 | -18.4% | 3 | -3 | $1,763 | $2,239,752 | 8 | United International Pictures | false | false |
| 17 | 7 | Revolver 2007 Re-release | $3,814 | -90.1% | 1 | -7 | $3,814 | $61,322 | 2 | Italian International Film | false | false |
| 18 | 18 | Up | $2,013 | -26% | 1 | - | $2,013 | $1,017,997 | 11 | Walt Disney Pictures | false | false |
| 19 | 19 | Land of the Lost | $1,857 | -12.8% | 1 | - | $1,857 | $554,410 | 6 | United International Pictures | false | false |
| 20 | 8 | Masjoun Transit | $1,826 | -95.1% | 1 | -14 | $1,826 | $54,205 | 2 | Gulf Film | false | false |
| 21 | 17 | My Bloody Valentine | $1,711 | -55.6% | 1 | - | $1,711 | $275,917 | 5 | Gulf Film | false | false |
| 22 | 12 | Public Enemies | $1,591 | -92.6% | 1 | -4 | $1,591 | $582,520 | 4 | United International Pictures | false | false |
| 23 | 16 | Ghosts of Girlfriends Past | $1,560 | -62.3% | 1 | -1 | $1,560 | $420,366 | 5 | Gulf Film | false | false |
| 24 | 21 | The Missing Lynx | $1,240 | +0.3% | 1 | - | $1,240 | $114,420 | 7 | Gulf Film | false | false |
| 25 | 13 | Che: Part Two | $1,099 | -92.1% | 1 | -11 | $1,099 | $20,752 | 2 | Gulf Film | false | false |
