| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inglourious Basterds | $28,347 | -37.4% | 5 | - | $5,669 | $116,434 | 2 | United International Pictures | false | false |
| 2 | 2 | Up | $17,475 | -5.1% | 8 | - | $2,184 | $210,391 | 4 | Walt Disney Pictures | false | false |
| 3 | - | G.I. Joe: The Rise of Cobra | $15,107 | - | 5 | - | $3,021 | $15,107 | 1 | United International Pictures | true | false |
| 4 | 3 | Ice Age: Dawn of the Dinosaurs | $7,175 | -18.6% | 5 | -1 | $1,435 | $1,138,968 | 9 | 20th Century Fox International | false | false |
| 5 | 6 | The Proposal | $6,144 | +7.4% | 4 | - | $1,536 | $6,144 | 7 | Walt Disney Pictures | false | false |
| 6 | 5 | District 9 | $5,431 | -20.6% | 2 | - | $2,715 | $57,264 | 3 | Sony Pictures Releasing | false | false |
| 7 | 4 | Spread | $4,461 | -42.4% | 1 | - | $4,461 | $20,050 | 2 | N/A | false | false |
| 8 | 7 | Harry Potter and the Half-Blood Prince | $4,459 | -17.2% | 5 | - | $891 | $216,589 | 6 | Warner Bros. | false | false |
| 9 | 8 | Two Lovers | $3,886 | +49.3% | 1 | - | $3,886 | $9,532 | 2 | N/A | false | false |
| 10 | 10 | The Hangover | $1,807 | +4.1% | 1 | - | $1,807 | $205,653 | 11 | Warner Bros. | false | false |
