| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | District 9 | $20,803 | - | 5 | - | $4,160 | $20,803 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Inglourious Basterds | $18,669 | -16.2% | 3 | - | $6,223 | $63,256 | 2 | - | false | false |
| 3 | - | High Security Vacation | $17,341 | - | 3 | - | $5,780 | $17,341 | 1 | ACME | true | false |
| 4 | 2 | Up | $15,308 | +7% | 9 | - | $1,700 | $168,066 | 4 | - | false | false |
| 5 | 3 | Spread | $8,359 | -21.3% | 1 | - | $8,359 | $38,644 | 2 | ACME | false | false |
| 6 | - | Broken Embraces | $6,967 | - | 2 | - | $3,483 | $6,967 | 1 | - | true | false |
| 7 | 4 | Ice Age: Dawn of the Dinosaurs | $6,926 | -9% | 12 | - | $577 | $752,191 | 9 | - | false | false |
| 8 | 6 | The Proposal | $5,393 | -9.4% | 3 | - | $1,797 | $160,563 | 8 | - | false | false |
| 9 | 5 | G.I. Joe: The Rise of Cobra | $3,784 | -42.5% | 3 | - | $1,261 | $52,052 | 3 | - | false | false |
| 10 | 7 | Harry Potter and the Half-Blood Prince | $3,776 | -22.1% | 6 | - | $629 | $227,452 | 6 | - | false | false |
| 11 | 8 | The Taking of Pelham 123 | $2,291 | -37% | 2 | - | $1,145 | $42,705 | 4 | Sony Pictures Releasing | false | false |
| 12 | 9 | Two Lovers | $2,133 | -31.2% | 1 | - | $2,133 | $25,773 | 3 | ACME | false | false |
| 13 | 10 | The Hangover | $1,791 | -28.6% | 3 | - | $597 | $211,192 | 12 | - | false | false |
| 14 | 11 | Public Enemies | $1,728 | -30.7% | 4 | - | $432 | $123,883 | 8 | - | false | false |
| 15 | 12 | Easy Virtue | $301 | -84.3% | 1 | - | $301 | $44,156 | 5 | - | false | false |
