| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Inglourious Basterds | $1,138,925 | - | 78 | - | $14,601 | $1,258,953 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Harry Potter and the Half-Blood Prince | $386,141 | -15.9% | 174 | -19 | $2,219 | $15,176,917 | 7 | Warner Bros. | false | false |
| 3 | 2 | The Taking of Pelham 123 | $267,928 | -25% | 70 | - | $3,827 | $833,639 | 2 | Sony Pictures Releasing | false | false |
| 4 | - | My Sister's Keeper | $248,200 | - | 37 | - | $6,708 | $257,220 | 1 | Warner Bros. | true | false |
| 5 | 3 | Ice Age: Dawn of the Dinosaurs | $213,463 | -9.6% | 168 | -28 | $1,270 | $11,926,364 | 9 | 20th Century Fox International | false | false |
| 6 | 6 | G-Force | $166,586 | +1% | 104 | -5 | $1,601 | $1,997,155 | 5 | Walt Disney Pictures | false | false |
| 7 | 4 | G.I. Joe: The Rise of Cobra | $143,013 | -36.1% | 80 | -2 | $1,787 | $1,124,450 | 3 | United International Pictures | false | false |
| 8 | 7 | The Girl with the Dragon Tattoo | $125,968 | +11% | 39 | +1 | $3,229 | $804,744 | 4 | Benelux Film Distributors | false | false |
| 9 | 5 | Public Enemies | $122,016 | -28.1% | 80 | - | $1,525 | $2,202,335 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | 8 | The Hangover | $94,114 | -10.7% | 52 | -5 | $1,809 | $4,801,753 | 12 | Warner Bros. | false | false |
| 11 | 9 | The Proposal | $84,633 | -13.5% | 60 | -7 | $1,410 | $4,044,920 | 11 | Walt Disney Pictures | false | false |
| 12 | - | Broken Embraces | $75,896 | - | 23 | - | $3,299 | $87,858 | 1 | Cinéart | true | false |
| 13 | - | Bandslam | $70,496 | - | 40 | - | $1,762 | $96,484 | 1 | Independent Films | true | false |
| 14 | 10 | Hannah Montana: The Movie | $59,106 | -24.7% | 30 | - | $1,970 | $213,030 | 2 | Walt Disney Pictures | false | false |
| 15 | 13 | Lilly the Witch: The Dragon and the Magic Book | $49,264 | +15.3% | 50 | - | $985 | $116,714 | 2 | RCV Film Distribution | false | false |
| 16 | 12 | Het geheim van Mega Mindy | $48,154 | -10.1% | 95 | -11 | $506 | $2,061,380 | 8 | Independent Films | false | false |
| 17 | 11 | A Perfect Getaway | $39,076 | -38.4% | 40 | -12 | $976 | $548,387 | 4 | A-Film Distribution | false | false |
| 18 | 17 | Mid-August Lunch | $36,679 | +13.5% | 11 | - | $3,334 | $112,235 | 2 | Cinemien | false | false |
| 19 | 16 | The Indian | $35,895 | +7.4% | 69 | -2 | $520 | $263,845 | 3 | A-Film Distribution | false | false |
| 20 | 15 | Luke and Lucy: The Texas Rangers | $34,525 | -2.8% | 86 | -1 | $401 | $723,726 | 6 | RCV Film Distribution | false | false |
