| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Orphan | $92,758 | -10.5% | 24 | - | $3,864 | $230,745 | 2 | Warner Bros. | false | false |
| 2 | - | Tinker Bell and the Lost Treasure | $64,504 | - | 33 | - | $1,954 | $64,504 | 1 | Walt Disney Pictures | true | false |
| 3 | - | The Ugly Truth | $61,809 | - | 25 | - | $2,472 | $61,809 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | The Hangover | $57,659 | -36.3% | 29 | +1 | $1,988 | $291,339 | 3 | Warner Bros. | false | false |
| 5 | 4 | Aliens in the Attic | $50,639 | -28.9% | 32 | +1 | $1,582 | $134,106 | 2 | 20th Century Fox International | false | false |
| 6 | 3 | G-Force | $47,685 | -34.6% | 40 | -4 | $1,192 | $1,368,474 | 7 | Walt Disney Pictures | false | false |
| 7 | 5 | The Maid | $28,172 | -49.1% | 20 | - | $1,408 | $318,609 | 4 | Andes Films | false | false |
| 8 | 7 | Last Chance Harvey | $21,961 | -39.4% | 10 | - | $2,196 | $65,741 | 2 | N/A | false | false |
| 9 | 6 | Ice Age: Dawn of the Dinosaurs | $19,125 | -47.8% | 32 | -11 | $597 | $6,853,305 | 10 | 20th Century Fox International | false | false |
| 10 | - | Boogeyman 2 | $17,196 | - | 14 | - | $1,228 | $17,196 | 1 | N/A | true | false |
| 11 | 9 | Public Enemies | $14,437 | -43.7% | 19 | -2 | $759 | $478,335 | 6 | United International Pictures | false | false |
| 12 | 8 | The Proposal | $12,987 | -53.9% | 19 | -5 | $683 | $270,534 | 5 | Walt Disney Pictures | false | false |
| 13 | 12 | Shorts | $11,575 | -36.8% | 18 | -7 | $643 | $213,581 | 5 | Warner Bros. | false | false |
| 14 | - | Che: Part Two | $8,761 | - | 7 | - | $1,251 | $8,761 | 1 | N/A | true | false |
| 15 | 13 | Harry Potter and the Half-Blood Prince | $7,865 | -55% | 15 | -166 | $524 | $3,480,066 | 8 | Warner Bros. | false | false |
| 16 | 10 | G.I. Joe: The Rise of Cobra | $7,784 | -68.9% | 19 | -17 | $409 | $414,186 | 5 | United International Pictures | false | false |
| 17 | - | The Visitor | $7,430 | - | 4 | - | $1,857 | $7,430 | 1 | N/A | true | false |
| 18 | 11 | My Bloody Valentine | $6,935 | -65% | 5 | -17 | $1,387 | $92,094 | 3 | N/A | false | false |
| 19 | 16 | Bangkok Dangerous | $5,811 | -1.3% | 13 | +3 | $447 | $79,383 | 4 | N/A | false | false |
| 20 | 14 | Transporter 3 | $5,172 | -69.1% | 10 | - | $517 | $26,464 | 2 | N/A | false | false |
| 21 | 15 | State of Play | $3,311 | -68.8% | 11 | -2 | $301 | $77,776 | 4 | United International Pictures | false | false |
| 22 | 17 | Up | $2,406 | -47.4% | 5 | -1 | $481 | $3,643,112 | 13 | Walt Disney Pictures | false | false |
| 23 | 18 | Grade 3 | $80 | -95.3% | 1 | -4 | $80 | $1,146,214 | 9 | N/A | false | false |
