| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Up | $45,259 | +13.3% | 8 | -2 | $5,657 | $118,122 | 2 | Walt Disney Pictures | false | false |
| 2 | 1 | Inglourious Basterds | $26,924 | -42.5% | 5 | - | $5,384 | $146,961 | 2 | United International Pictures | false | false |
| 3 | - | Reykjavik Whale Watching Massacre | $16,221 | - | 5 | - | $3,244 | $16,221 | 1 | N/A | true | false |
| 4 | 3 | The Girl with the Dragon Tattoo | $6,301 | -36.7% | 4 | - | $1,575 | $289,150 | 7 | N/A | false | false |
| 5 | - | Halloween II | $5,444 | - | 2 | - | $2,722 | $5,444 | 1 | N/A | true | false |
| 6 | 5 | The Proposal | $4,954 | -2.8% | 4 | -2 | $1,238 | $219,214 | 6 | Walt Disney Pictures | false | false |
| 7 | 9 | Ice Age: Dawn of the Dinosaurs | $3,767 | +46.5% | 6 | -1 | $627 | $265,671 | 10 | 20th Century Fox International | false | false |
| 8 | 4 | Drag Me to Hell | $3,456 | -54.9% | 2 | -1 | $1,728 | $64,395 | 3 | N/A | false | false |
| 9 | 10 | G-Force | $3,204 | +24.7% | 2 | -2 | $1,602 | $112,898 | 5 | Walt Disney Pictures | false | false |
| 10 | 6 | The Taking of Pelham 123 | $2,613 | -31.7% | 3 | -1 | $871 | $35,623 | 3 | Sony Pictures Releasing | false | false |
| 11 | - | The September Issue | $2,095 | - | 1 | - | $2,095 | $2,095 | 1 | N/A | true | false |
| 12 | 7 | G.I. Joe: The Rise of Cobra | $2,052 | -38.4% | 3 | -2 | $684 | $73,346 | 4 | United International Pictures | false | false |
| 13 | 11 | The Time Traveler's Wife | $1,970 | -16.4% | 1 | -1 | $1,970 | $14,593 | 3 | N/A | false | false |
| 14 | 13 | Harry Potter and the Half-Blood Prince | $1,960 | +121.7% | 1 | -1 | $1,960 | $321,256 | 8 | Warner Bros. | false | false |
| 15 | 12 | The Goods: Live Hard, Sell Hard | $1,543 | -8.3% | 2 | - | $771 | $17,405 | 3 | N/A | false | false |
| 16 | 8 | Public Enemies | $1,017 | -64.4% | 2 | -3 | $508 | $141,273 | 5 | United International Pictures | false | false |
| 17 | 15 | My Sister's Keeper | $636 | +8.3% | 1 | - | $636 | $91,088 | 9 | N/A | false | false |
| 18 | 14 | The Hangover | $175 | -79.8% | 1 | - | $175 | $409,414 | 13 | Warner Bros. | false | false |
