| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Up | $27,991 | -38.2% | 9 | +1 | $3,110 | $155,824 | 3 | Walt Disney Pictures | false | false |
| 2 | - | The Final Destination | $27,991 | - | 4 | - | $6,997 | $27,991 | 1 | N/A | true | false |
| 3 | 2 | Inglourious Basterds | $17,094 | -36.5% | 5 | - | $3,418 | $185,028 | 3 | United International Pictures | false | false |
| 4 | 4 | The Girl with the Dragon Tattoo | $8,294 | +31.6% | 4 | - | $2,073 | $303,359 | 8 | N/A | false | false |
| 5 | 3 | Reykjavik Whale Watching Massacre | $6,017 | -62.9% | 5 | - | $1,203 | $34,949 | 2 | N/A | false | false |
| 6 | - | Bandslam | $4,648 | - | 3 | - | $1,549 | $4,648 | 1 | N/A | true | false |
| 7 | - | Beyond a Reasonable Doubt | $3,695 | - | 2 | - | $1,847 | $3,721 | 1 | N/A | true | false |
| 8 | 7 | Ice Age: Dawn of the Dinosaurs | $3,144 | -16.5% | 5 | -1 | $628 | $268,981 | 11 | 20th Century Fox International | false | false |
| 9 | 6 | The Proposal | $2,465 | -50.2% | 3 | -1 | $821 | $225,179 | 7 | Walt Disney Pictures | false | false |
| 10 | 8 | Drag Me to Hell | $2,462 | -28.8% | 2 | - | $1,231 | $69,407 | 4 | N/A | false | false |
| 11 | 9 | G-Force | $2,399 | -25.1% | 4 | +2 | $599 | $115,738 | 6 | Walt Disney Pictures | false | false |
| 12 | 5 | Halloween II | $1,919 | -64.8% | 2 | - | $959 | $11,213 | 2 | N/A | false | false |
| 13 | 11 | The September Issue | $1,521 | -27.4% | 1 | - | $1,521 | $5,964 | 2 | N/A | false | false |
| 14 | 12 | G.I. Joe: The Rise of Cobra | $833 | -59.4% | 1 | -2 | $833 | $75,827 | 5 | United International Pictures | false | false |
| 15 | 15 | The Goods: Live Hard, Sell Hard | $785 | -49.1% | 1 | -1 | $785 | $19,895 | 4 | N/A | false | false |
| 16 | 14 | Harry Potter and the Half-Blood Prince | $765 | -61% | 1 | - | $765 | $322,343 | 9 | Warner Bros. | false | false |
| 17 | 10 | The Taking of Pelham 123 | $717 | -72.6% | 2 | -1 | $358 | $38,810 | 4 | Sony Pictures Releasing | false | false |
| 18 | 17 | My Sister's Keeper | $632 | -0.6% | 1 | - | $632 | $92,493 | 10 | N/A | false | false |
