| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Ugly Truth | $35,788 | - | 7 | - | $5,112 | $47,220 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | The Final Destination | $28,597 | -53.3% | 6 | - | $4,766 | $124,404 | 2 | - | false | false |
| 3 | 2 | Up | $23,195 | -31.6% | 12 | - | $1,932 | $370,986 | 4 | Universal Pictures International (UPI) | false | false |
| 4 | 4 | Inglourious Basterds | $13,890 | -35.1% | 6 | - | $2,315 | $119,087 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 3 | High Security Vacation | $9,268 | -57% | 4 | - | $2,317 | $38,385 | 2 | ACME | false | false |
| 6 | 5 | Vortex | $5,646 | -39.2% | 3 | - | $1,882 | $20,311 | 14 | N/A | false | false |
| 7 | 8 | My Sister's Keeper | $4,328 | -28.5% | 4 | - | $1,082 | $105,652 | 6 | - | false | false |
| 8 | 7 | Ice Age: Dawn of the Dinosaurs | $3,684 | -47.9% | 5 | -2 | $736 | $1,413,616 | 11 | Universal Pictures International (UPI) | false | false |
| 9 | 6 | District 9 | $3,119 | -61.4% | 7 | - | $445 | $93,756 | 5 | Sony Pictures Releasing | false | false |
| 10 | 11 | G.I. Joe: The Rise of Cobra | $1,258 | -44.8% | 4 | - | $314 | $54,563 | 5 | Universal Pictures International (UPI) | false | false |
| 11 | - | Dream | $1,124 | - | 1 | - | $1,124 | $1,124 | 1 | N/A | true | false |
| 12 | 9 | Harry Potter and the Half-Blood Prince | $900 | -71.8% | 7 | - | $128 | $321,599 | 8 | Garsu Pasaulio Irasai | false | false |
| 13 | 10 | Diary of a Nymphomaniac | $765 | -70.3% | 2 | - | $382 | $34,606 | 6 | ACME | false | false |
| 14 | - | The Last House on the Left | $649 | - | 2 | - | $324 | $30,227 | 8 | Universal Pictures International (UPI) | false | false |
| 15 | 15 | Let the Right One In | $334 | +10.6% | 1 | - | $334 | $8,961 | 4 | Universal Pictures International (UPI) | false | false |
| 16 | - | Hannah Montana: The Movie | $327 | - | 1 | - | $327 | $30,328 | 7 | Universal Pictures International (UPI) | false | false |
| 17 | 17 | Lorna's Silence | $177 | -22.4% | 1 | - | $177 | $2,518 | 3 | N/A | false | false |
| 18 | 12 | Year One | $103 | -85.2% | 2 | - | $51 | $77,300 | 2 | Sony Pictures Releasing | false | false |
| 19 | 18 | Bolt | $48 | -78.3% | 2 | - | $24 | $347,482 | 29 | Universal Pictures International (UPI) | false | false |
| 20 | - | The Proposal | $46 | - | 1 | - | $46 | $162,068 | 13 | Universal Pictures International (UPI) | false | false |
