| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Final Destination | $187,602 | -13.5% | 57 | - | $3,291 | $499,299 | 2 | Cine Colombia | false | false |
| 2 | 2 | The Taking of Pelham 123 | $116,715 | -19% | 56 | - | $2,084 | $311,936 | 2 | Sony Pictures Releasing | false | false |
| 3 | 3 | Aliens in the Attic | $70,044 | -3.3% | 43 | -2 | $1,628 | $158,658 | 2 | 20th Century Fox International | false | false |
| 4 | 4 | The Ugly Truth | $69,888 | -2.5% | 40 | - | $1,747 | $490,462 | 4 | Sony Pictures Releasing | false | false |
| 5 | 5 | G-Force | $44,094 | -20.4% | 80 | -12 | $551 | $2,395,250 | 8 | Walt Disney Pictures | false | false |
| 6 | 6 | The Hangover | $37,867 | -23.2% | 55 | -2 | $688 | $797,194 | 6 | Warner Bros. | false | false |
| 7 | 7 | The Accidental Husband | $37,827 | -16.7% | 32 | -1 | $1,182 | $98,307 | 2 | Walt Disney Pictures | false | false |
| 8 | 8 | Shorts | $36,494 | -9.1% | 43 | -1 | $848 | $249,208 | 4 | Warner Bros. | false | false |
| 9 | 9 | Orphan | $33,941 | -8.9% | 54 | +10 | $628 | $456,168 | 5 | Warner Bros. | false | false |
| 10 | 10 | Public Enemies | $25,335 | -15.6% | 46 | +1 | $550 | $434,497 | 5 | United International Pictures | false | false |
| 11 | 12 | The Uninvited | $20,282 | +2.4% | 26 | +1 | $780 | $109,624 | 3 | United International Pictures | false | false |
| 12 | 11 | The Reader | $19,771 | -9% | 13 | - | $1,520 | $52,904 | 2 | Cineplex | false | false |
| 13 | 13 | Ice Age: Dawn of the Dinosaurs | $11,179 | -22.3% | 46 | -4 | $243 | $7,744,080 | 12 | 20th Century Fox International | false | false |
| 14 | - | The Killing Gene | $11,015 | - | 16 | - | $688 | $11,015 | 1 | Cine Colombia | true | false |
| 15 | 15 | My Bloody Valentine | $8,504 | +18% | 6 | -3 | $1,417 | $327,140 | 6 | Cine Colombia | false | false |
| 16 | - | The Good Night | $7,251 | - | 11 | - | $659 | $7,251 | 1 | Cine Colombia | true | false |
| 17 | 14 | G.I. Joe: The Rise of Cobra | $5,207 | -48.8% | 15 | -11 | $347 | $920,882 | 7 | United International Pictures | false | false |
| 18 | 16 | The Bank Job | $4,717 | -2.7% | 8 | -5 | $589 | $210,267 | 8 | Cine Colombia | false | false |
| 19 | 17 | The Proposal | $2,617 | -40.5% | 4 | -3 | $654 | $839,986 | 11 | Walt Disney Pictures | false | false |
| 20 | 22 | Transporter 3 | $2,546 | +59.2% | 5 | +3 | $509 | $295,442 | 15 | Cineplex | false | false |
| 21 | 19 | Harry Potter and the Half-Blood Prince | $1,926 | -26.4% | 7 | -3 | $275 | $2,824,655 | 10 | Warner Bros. | false | false |
| 22 | 18 | Elegy | $1,565 | -60% | 7 | - | $223 | $94,438 | 11 | Cine Colombia | false | false |
| 23 | 24 | The Last House on the Left | $1,546 | +12.5% | 3 | - | $515 | $151,276 | 11 | United International Pictures | false | false |
| 24 | 20 | Be Kind Rewind | $1,149 | -53.6% | 4 | -2 | $287 | $4,595 | 2 | Cine Colombia | false | false |
| 25 | 23 | In Bruges | $1,149 | -16.4% | 3 | -1 | $383 | $23,144 | 3 | Cine Colombia | false | false |
| 26 | 25 | Donkey Xote | $603 | -28.3% | 3 | -4 | $201 | $17,720 | 6 | Cine Colombia | false | false |
| 27 | 21 | State of Play | $592 | -67.6% | 1 | -4 | $592 | $184,798 | 8 | United International Pictures | false | false |
