| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Final Destination | $36,070 | - | 1 | - | $36,070 | $36,070 | 1 | - | true | false |
| 2 | 4 | High Security Vacation | $8,735 | +4.7% | 2 | - | $4,367 | $69,256 | 4 | ACME | false | false |
| 3 | 3 | Up | $8,472 | -18.7% | 9 | - | $941 | $227,492 | 7 | - | false | false |
| 4 | 2 | Inglourious Basterds | $7,860 | -30.7% | 3 | - | $2,620 | $135,619 | 5 | - | false | false |
| 5 | 7 | The Proposal | $5,411 | -2.2% | 3 | - | $1,803 | $198,668 | 11 | - | false | false |
| 6 | 1 | Gamer | $5,299 | -56.6% | 2 | - | $2,649 | $24,160 | 2 | ACME | false | false |
| 7 | 6 | Spread | $4,488 | -28.3% | 1 | - | $4,488 | $78,725 | 5 | ACME | false | false |
| 8 | - | Taking Woodstock | $4,207 | - | 1 | - | $4,207 | $4,207 | 1 | ACME | true | false |
| 9 | 11 | Broken Embraces | $3,555 | -4.6% | 2 | - | $1,777 | $37,602 | 4 | - | false | false |
| 10 | 5 | District 9 | $3,276 | -48.1% | 5 | - | $655 | $72,150 | 4 | Sony Pictures Releasing | false | false |
| 11 | 12 | The Hangover | $2,883 | -8.4% | 3 | - | $961 | $230,638 | 15 | - | false | false |
| 12 | 8 | Coraline | $2,881 | -39.8% | 1 | - | $2,881 | $22,636 | 3 | - | false | false |
| 13 | 9 | Whatever Works | $2,195 | -48.5% | 1 | - | $2,195 | $20,373 | 3 | - | false | false |
| 14 | - | District 13: Ultimatum | $2,153 | - | 1 | - | $2,153 | $2,153 | 1 | N/A | true | false |
| 15 | 10 | Ice Age: Dawn of the Dinosaurs | $2,139 | -44.9% | 12 | - | $178 | $792,504 | 12 | - | false | false |
| 16 | 13 | Harry Potter and the Half-Blood Prince | $1,440 | -43.5% | 6 | - | $240 | $248,244 | 9 | - | false | false |
