| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Ugly Truth | $10,827 | -37.8% | 6 | - | $1,804 | $46,928 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Up | $9,142 | - | 6 | - | $1,523 | $16,788 | 1 | Walt Disney Pictures | true | false |
| 3 | - | The Final Destination | $8,814 | - | 4 | - | $2,203 | $10,864 | 1 | Warner Bros. | true | false |
| 4 | 3 | Ice Age: Dawn of the Dinosaurs | $7,928 | -18.6% | 9 | - | $880 | $386,930 | 12 | 20th Century Fox International | false | false |
| 5 | 2 | Inglourious Basterds | $6,681 | -53.7% | 6 | - | $1,113 | $147,308 | 5 | United International Pictures | false | false |
| 6 | 7 | Harry Potter and the Half-Blood Prince | $3,391 | +95.6% | 8 | - | $423 | $190,434 | 10 | Warner Bros. | false | false |
| 7 | 4 | The Taking of Pelham 123 | $2,113 | -53.6% | 5 | - | $422 | $31,124 | 4 | Sony Pictures Releasing | false | false |
| 8 | 5 | G-Force | $1,594 | -59.6% | 5 | - | $318 | $25,233 | 4 | Walt Disney Pictures | false | false |
| 9 | 6 | The Proposal | $1,419 | -35.1% | 6 | - | $236 | $105,076 | 9 | Walt Disney Pictures | false | false |
| 10 | 9 | Public Enemies | $502 | -60.8% | 5 | - | $100 | $76,305 | 12 | United International Pictures | false | false |
| 11 | 10 | The Hangover | $460 | -35.8% | 5 | - | $92 | $141,624 | 14 | Warner Bros. | false | false |
| 12 | 14 | Coraline | $414 | -7.6% | 4 | - | $103 | $34,862 | 16 | United International Pictures | false | false |
| 13 | 8 | Two Lovers | $251 | -83.3% | 3 | - | $83 | $11,842 | 4 | N/A | false | false |
| 14 | 16 | Hannah Montana: The Movie | $238 | +10.7% | 5 | - | $47 | $32,730 | 15 | Walt Disney Pictures | false | false |
| 15 | 12 | Superhero Movie | $183 | -69.7% | 1 | - | $183 | $2,722 | 3 | N/A | false | false |
| 16 | 13 | Knowing | $156 | -72.1% | 4 | - | $39 | $26,618 | 8 | N/A | false | false |
| 17 | 20 | Terminator Salvation | $113 | +162.8% | 2 | - | $56 | $91,851 | 16 | Sony Pictures Releasing | false | false |
| 18 | - | State of Play | $32 | - | 4 | - | $8 | $31,083 | 15 | United International Pictures | false | false |
| 19 | 15 | Brüno | $31 | -85.6% | 6 | - | $5 | $64,637 | 11 | N/A | false | false |
