| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Fame | $3,840,468 | - | 459 | - | $8,367 | $3,840,468 | 1 | Entertainment Film Distributors | true | false |
| 2 | 1 | Cloudy with a Chance of Meatballs | $2,237,157 | -13.1% | 438 | - | $5,107 | $5,480,471 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | Surrogates | $1,532,956 | - | 356 | - | $4,306 | $1,532,956 | 1 | Walt Disney Pictures | true | false |
| 4 | 2 | District 9 | $891,382 | -32.4% | 399 | -54 | $2,234 | $11,942,381 | 4 | Sony Pictures Releasing | false | false |
| 5 | - | The Soloist | $595,071 | - | 351 | - | $1,695 | $595,071 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | 500 Days of Summer | $538,278 | -35.2% | 300 | -24 | $1,794 | $6,428,273 | 4 | 20th Century Fox International | false | false |
| 7 | 5 | The Final Destination | $518,803 | -34.4% | 254 | -75 | $2,042 | $19,696,791 | 5 | Entertainment Film Distributors | false | false |
| 8 | 6 | Dorian Gray | $372,588 | -47.5% | 302 | -47 | $1,233 | $3,747,527 | 3 | Momentum Pictures | false | false |
| 9 | 3 | Gamer | $334,580 | -67.9% | 313 | -33 | $1,068 | $1,883,440 | 2 | Entertainment Film Distributors | false | false |
| 10 | - | Creation | $318,110 | - | 236 | - | $1,347 | $318,110 | 1 | Icon Film Distribution | true | false |
| 11 | 7 | Julie & Julia | $293,522 | -53.7% | 242 | -115 | $1,212 | $3,231,829 | 3 | Sony Pictures Releasing | false | false |
| 12 | 8 | Sorority Row | $264,149 | -53.3% | 245 | -104 | $1,078 | $2,910,442 | 3 | Entertainment One | false | false |
| 13 | 9 | The Firm | $227,292 | -54.9% | 230 | -35 | $988 | $1,094,777 | 2 | Warner Bros. | false | false |
| 14 | 12 | Aliens in the Attic | $223,892 | -28.4% | 363 | -62 | $616 | $10,250,055 | 8 | 20th Century Fox International | false | false |
| 15 | 11 | Inglourious Basterds | $199,375 | -48.5% | 130 | -121 | $1,533 | $16,439,434 | 6 | Universal Pictures International (UPI) | false | false |
