| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Big Rescue | $55,871 | - | 8 | - | $6,983 | $55,871 | 1 | N/A | true | false |
| 2 | 1 | The Ugly Truth | $20,077 | -50.3% | 5 | - | $4,015 | $90,933 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | Funny People | $11,176 | - | 3 | - | $3,725 | $12,088 | 1 | United International Pictures | true | false |
| 4 | 2 | District 9 | $11,164 | -62.8% | 4 | - | $2,791 | $70,789 | 2 | N/A | false | false |
| 5 | 3 | Up | $9,717 | -51.3% | 5 | -5 | $1,943 | $194,443 | 5 | Walt Disney Pictures | false | false |
| 6 | 4 | The Girl with the Dragon Tattoo | $7,693 | -31.8% | 4 | - | $1,923 | $337,563 | 10 | N/A | false | false |
| 7 | - | Jennifer's Body | $5,161 | - | 3 | - | $1,720 | $5,161 | 1 | 20th Century Fox International | true | false |
| 8 | 5 | Inglourious Basterds | $3,758 | -58.6% | 2 | -2 | $1,879 | $215,960 | 5 | United International Pictures | false | false |
| 9 | - | The Haunting in Connecticut | $2,063 | - | 2 | - | $1,031 | $2,063 | 1 | N/A | true | false |
| 10 | - | Bionicle: The Legend Reborn | $1,684 | - | 3 | - | $561 | $1,684 | 1 | N/A | true | false |
| 11 | 6 | The Final Destination | $1,446 | -83% | 2 | -1 | $723 | $59,576 | 3 | N/A | false | false |
| 12 | 10 | Ice Age: Dawn of the Dinosaurs | $1,342 | -35.4% | 2 | -3 | $671 | $272,700 | 13 | 20th Century Fox International | false | false |
| 13 | 14 | Harry Potter and the Half-Blood Prince | $1,274 | +140.8% | 2 | +1 | $637 | $324,576 | 11 | Warner Bros. | false | false |
| 14 | 7 | Bandslam | $918 | -69.2% | 1 | -2 | $918 | $12,387 | 3 | N/A | false | false |
| 15 | 8 | G-Force | $879 | -68% | 2 | -1 | $439 | $119,463 | 8 | Walt Disney Pictures | false | false |
| 16 | 9 | Reykjavik Whale Watching Massacre | $376 | -85.7% | 4 | -1 | $94 | $42,752 | 4 | N/A | false | false |
| 17 | 11 | The Proposal | $208 | -83.4% | 1 | - | $208 | $229,159 | 9 | Walt Disney Pictures | false | false |
| 18 | 12 | Drag Me to Hell | $168 | -80.1% | 1 | -1 | $168 | $70,994 | 6 | N/A | false | false |
| 19 | 16 | Halloween II | $48 | -61.6% | 1 | - | $48 | $12,334 | 4 | N/A | false | false |
| 20 | 13 | Beyond a Reasonable Doubt | $48 | -92.4% | 1 | - | $48 | $8,343 | 3 | N/A | false | false |
