| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Storm | $867,507 | +36.5% | 110 | -1 | $7,886 | $1,797,772 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | Inglourious Basterds | $468,612 | -2.1% | 80 | - | $5,857 | $5,040,300 | 5 | Universal Pictures International (UPI) | false | false |
| 3 | - | Lover or Loser | $355,764 | - | 99 | - | $3,593 | $408,194 | 1 | RCV Film Distribution | true | false |
| 4 | 3 | The Final Destination | $242,270 | -17.5% | 55 | -1 | $4,404 | $2,061,912 | 4 | Warner Bros. | false | false |
| 5 | - | The Rebound | $226,931 | - | 62 | - | $3,660 | $380,001 | 1 | Paradiso Entertainment | true | false |
| 6 | - | Dance Flick | $158,972 | - | 26 | - | $6,114 | $187,612 | 1 | Universal Pictures International (UPI) | true | false |
| 7 | 6 | G-Force | $150,423 | +20.5% | 105 | - | $1,432 | $2,845,628 | 9 | Walt Disney Pictures | false | false |
| 8 | 4 | My Sister's Keeper | $122,546 | -16.9% | 38 | -1 | $3,224 | $1,192,667 | 5 | Warner Bros. | false | false |
| 9 | 8 | Ice Age: Dawn of the Dinosaurs | $116,717 | +14% | 117 | -7 | $997 | $12,936,526 | 13 | 20th Century Fox International | false | false |
| 10 | 7 | The Taking of Pelham 123 | $108,940 | -5% | 58 | -10 | $1,878 | $1,602,231 | 6 | Sony Pictures Releasing | false | false |
| 11 | 5 | Harry Potter and the Half-Blood Prince | $101,543 | -27.3% | 98 | -36 | $1,036 | $16,543,906 | 11 | Warner Bros. | false | false |
| 12 | - | Carriers | $86,737 | - | 30 | - | $2,891 | $117,394 | 1 | Independent Films | true | false |
| 13 | 9 | The Girl with the Dragon Tattoo | $70,351 | -4.3% | 33 | -4 | $2,131 | $1,353,194 | 8 | Benelux Film Distributors | false | false |
| 14 | - | 500 Days of Summer | $60,289 | - | 15 | - | $4,019 | $79,326 | 1 | Warner Bros. | true | false |
| 15 | 14 | Lilly the Witch: The Dragon and the Magic Book | $55,896 | +51% | 39 | -11 | $1,433 | $381,960 | 6 | RCV Film Distribution | false | false |
| 16 | 10 | The Hangover | $50,565 | -16.3% | 34 | -14 | $1,487 | $5,279,305 | 16 | Warner Bros. | false | false |
| 17 | 13 | Broken Embraces | $33,893 | -11.8% | 22 | +1 | $1,540 | $382,877 | 5 | Cinéart | false | false |
| 18 | 12 | The Proposal | $32,421 | -32.1% | 53 | - | $611 | $4,433,562 | 15 | Walt Disney Pictures | false | false |
| 19 | 11 | Funny People | $24,803 | -57% | 18 | -12 | $1,377 | $383,301 | 4 | Universal Pictures International (UPI) | false | false |
| 20 | 15 | Princess Lillifee | $24,636 | -11.1% | 21 | - | $1,173 | $67,794 | 2 | Benelux Film Distributors | false | false |
